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Title Section, List of contents, Author index and Subject index
NEUROCHEMISTRY INTERNATIONAL The Journal for the publication of cellular and molecular aspects of neurochemistry in the form of original and rapid research communications and also critical reviews and commentaries
Title Section, List of Contents Author and Subject Index Volume 1 5 (1 989)
PERGAMON PRESS Oxford
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NEUROCHEMISTRY INTERNATIONAL The Journal for the publication of cellular and molecular aspects of neurochemistry in the form of original and rapid research communications and also critical reviews and commentaries E x e c u t i v e Editors For U.K. Also for Reviews, Commentaries and Rapid Reports N. N. Osborne (Chairman): NuffieM Laboratory of Ophthalmology, University of Oxford, Walton Street, Oxford 0)(2 6,414I, U.K. For Europe and Africa: J. Rossier: CNRS Laboratoire de Physiologie Nerveuse, 91190 Gifs u r - Yvette, F r a n c e
For Australasia: G. A. R. Johnston: Department of Pharmacology, University q[" Sydney, Sydney, N S W 2006, Australia
For The Americas: W. Lovenberg: MerrelI-Dow Research Institute, 2110 E. Galbraith Road, Cincinnati, OH 45215, U.S.A. R. Tapia: Instituto de Fisiologia Celular, Universidad Nacional Autonoma, AP 70-600, 04510 Mexico D.F., Mex&o For Asia: K. Kuriyama: Department of Pharmacology, Kyoto Prefectural Universit)' of Medicine, Kawaramachi-Hirokoji, Kamikyo-ku, Kyoto, Japan
Editorial A d v i s o r y B o a r d A. A. AbdeI-Latif, Augusta, Ga R. Balazs, Amsterdam F.J. Barrantes, Argentina T. BartIai, Stockholm J. M, l ~ r r e , Paris H. Breer, Stuttgart S . H . Buck, Cincinnati, Ohio !. Creese, Newark, N.J. W . E . Davies, Birmingham, U.K. J. O. Dolly, London, U.K. G . J . Dockray, Liverpool, U.K. M. Ebadi, Omaha, Neb. M. Fillenz, Oxford, U.K. R. W. Fuller, Indianapolis, Ind. K. G. Fuxe, Stockholm M. Hamon, Paris R. B. Holman, Bristol, U.K. R . J . Huxtable, Tucson, Ariz. M. Israel, Gif-sur-Yvette P . M . luvone, Atlanta, Ga D.M. Jacobowitz, Bethesda, Aid G. Jaim-Eteheverry, Buenos Aires B. Jarrott, Melbourne J. W. Kebubian, Abbott Park, Ill. D. M. Kuhn, Detroit, Mich. P. J. Magistretti, Lausanne A.J. Mandell, La Jolla, Calif. D. Man-Kit Lain, Houston, Tex. N. Morel, Gif-sur- Yvette A. H. Molder, Amsterdam M . R . V . Murthy, Quebec T. Nagatsu, Nagoya N.H. Neff, Columbus, Ohio J . L . Nussbaum, Strasbourg B. Oderfeld-Nowak, Warsaw S.E. Poduslo, Baltimore, Md J.F. Pujol, Lyon M. Raiteri, Genoa S. Rose, Milton Keynes, U.K. R. H. Rotb, New Haven, Conn. E. Sanders-Bush, Nashville, Tenn. M. Satake, Niigata A. Schonsboe, Copenhagen J . E . Schultz, Tfibingen C.R. Snell, London, U.K. T . L . Sourkes, Montreal R. Tanaka, Nagoya G. Tettamanti, Milan P. M. Vanhoutte, Houston, Tex. J. J. Vanderhaeghen, Brussels J.-Y. Wu, Lawrence, Kan. M . B . H . Youdlm, Haifa H. Zimmermann, Frankfurt Aims and Scope: Neurochemistry International publishes (within 5 months of acceptance) papers primarily concerned with the metabolism and function of the nervous system. Papers are also published which deal with the chemical aspects of the anatomy, pathology, physiology, pharmacology and genetics of the nervous system, as well as the biochemistry of the nervous tissues. The journal also publishes material showing the relationship of fundamental neurochemical observations to basic neurology, neuropharmacology, chemical pathology and neurotransmission of the nervous system. The Executive Editors and Publisher would welcome comments from authors concerning improvements and/or clarification on the aims and scope of the journal.
Publishing Office: Journals Production Unit, Pergamon Press plc, Hennock Road, Marsh Barton, Exeter, Devon EX2 8NE, U.K. (Tel. Exeter (0392) 51558; Telex 42749) Subscription and Advertising Offices: Rest of the World, Pergamon Press plc, Headington Hill Hall, Oxford OX3 0BW, U.K. (Tel. Oxford (0865) 64881; Telex 83177). North America, Pergamon Press Inc., Maxwell House, Fairview Park Elmsford, N Y 10523, U.S.A. Subscription Rates (1990): Annual institutional rate (1990) DM 670.00; 2-year institutional rate (1990/91) DM 1273.00; personal subscription rate for those whose library subscribes at the regular rate (1990) DM t65.00. Special rates for members of the International Society for Neurochemistry and the European Society for Neurochemistry are available on request. All prices are subject to amendment without notice. Ba~k Issues: Back issues of all previously published volumes, in both hard copy and on microform, are available direct from Pergamon Press offices.
Publication Frequency: 2 volumes of 4 issues per volume Copyright ~: 1990. Pergamon Press plc It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. By submitting a manuscript, the authors agree that the copyright for their article is transferred to the copyright owner if and when the article is accepted for publication. However, assignment of copyright is not required from authors who work for organizations which do not permit such assignment. The copyright covers the exclusive rights to reproduce and distribute the article, including reprints, photographic reproductions, microform or any other reproductions of similar nature and translations. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, electrostatic. magnetic tape, mechanical, photocopying, recording or otherwise, without permission in writing from the copyright holder. Photocopying information for users in the U.S.A. The ltem-fec Code for this publication indicates that authorization to photocopy items for internal or personal use is granted by the copyright holder for libraries and other users registered with the Copyright Clearance Center (CCC) Transactional Reporting Service provided the stated fee for copying, beyond that permitted by Section 107 or t08 of the United States Copyright Law, is paid. The appropriate remittance of $3.00 per copy per article is paid directly to the Copyright Clearance Center Inc., 21 Congress Street, Salem, MA 01970. Permission for other use. The copyright owner's consent does not extend to copying for general distribution, for promotion, for creating new works, or for resale. Specific written permission must be obtained from the publisher for such copying. The Item-fee Code for this publication is: 0197-0186/90 $3.00+0.00.
LIST OF CONTENTS VOLUME
15 ( 1 9 8 9 )
Number 1 A. Doble and M. L. Perrier
Pharmacology of excitatory amino acid receptors coupled to inositol phosphate metabolism in neonatal rat striatum
Lia Prado de Carvalho
Modulation of acetylcholine release in rat striatal slices by muscarinic receptors which do not desensitize
Yukio Yoneda, Kiyokazu Ogita, Kisa Yamada, Tomoko Kouda, Takao Ohgaki, Shuji Uchida and Haruo Meguri
17 High concentrations of calmodulin antagonists inhibit accumulation and binding activities of [3H]glutamate in rat brain
P. T.-H. Wong, H. S. Lee, C. H. Tan and W.L. Teo
25
Specific [3H]tryptophan binding sites in rat brain
Masaaki Hirouchi, Ryozo Kuwano, Takashi Katagiri, Yasuo Takahashi and Kinya Kuriyama
33
Nucleotide and deduced amino acid sequences of the GABA A receptor ~t-subunit from human brain
P. P. De Deyn, B. A. Pickut, A. Verzwijvelen, R. D'Hooge, W. Annaert and W. P. De Potter
39 Subcellular distribution and axonal transport of noradrenaline, dopamine-fl-hydroxylase and neuropeptide Y in dog splenic nerve
R. M. Dawson, P. J. Gray, C. M. Upsher and S. Michaelson
49
Katsumichi Takeda, Fumiaka Uchiumi, Masatoshi Takita and Takeshi Kato
55 A rapid enzyme immunoassay for cholectystokinin octapeptide sulfate
Anthony Heape, Fran¢oise Boiron and Claude Cassagne
61
High uptake and rapid metabolism of palmitate in peripheral nerves of normal and Trembler mice in vivo: similarities and differences
Christopher J. Fowler, Cora O'Neill, Per Almqvist, Sofie Nilsson, Birgitta Wiehager and Bengt Winblad
73
Muscarinic receptors coupled to inositol phospholipid breakdown in human SH-SY5Y neuroblastoma cells: effect of retinoic acid-induced differentiation
Sherwin Wilk and Elizabeth K. Wilk
81
Pyroglutamyl peptidase II, a thyrotropin releasing hormone degrading enzyme: purification and specificity studies of the rabbit brain enzyme
G. F. Dunglison, P. A. Wilce and B. C. Shanley
91
Autoradiographic studies on the effect of ethanol on muscarinic receptors in rat brain
Alejandro M. Dopico, Luis M. Zieher, Jos6 Mayo, Noe Altsehiiller, Juan J. L6pez and Guillermo Jaim-Etcheverry
97
Long-term changes in noradrenaline (NA) and dopamine (DA) contents of rat cerebellum following neonatal X-irradiation
L. F. Agnati, K. Fuxe, M. Ruggeri, E. Merlo Pith, F. Benfenati, V. Volterra, U. Ungerstedt and I. Zini
Modification of the kinetic properties of Triton-solubilized rabbit brain acetylcholinesterase by allosteric effectors at low ionic strength
107 Effects of chronic treatment with uridine on striatal dopamine release and dopamine related behaviours in the absence or the presence of chronic treatment with haloperidol iii
Index
iv
Paula Rosario, Ana Barat and Galo Ramirez
115 Characterization of binding sites for [3H]GABA in Drosophila melanogaster CNS membranes 121
Book Reviews
125
News Items
Number 2 Jacqueline M. Evans and Gerald Cohen
127 Commentary: Can trace amounts of neurotoxins destroy dopamine neurons?
Darryle D. Schoepp
131
Yukio Yoneda and Kiyokazu Ogita
137 Characterization of quisqualate-sensitive [3H]glutamate activity solubilized from rat adrenal
Bertrand Lambolez, Claude-Marguerite Deschamps and Jean Rossier
145
Interactions of benzodiazepines and /~-carbolines with a histidine residue of the benzodiazepine receptor
K. Gulya, D. Budai and P. K~isa
153
Muscarinic autoreceptors are differentially affected by selective muscarinic antagonists in rat hippocampus
Z. Rakonczay, P. K~sa and J. R. Wolff
157 Change in the distribution of acetylcholinesterase molecular forms in the rat superior cervical ganglion after NaBr treatment in t,it,o
M. Garcia-Gil, E. Tongiorgi, M. Cattani, G. Cipollini and M. Brunelli
161
cAMP-dependent protein phosphorylation of a 79 kDa protein in segmental ganglia of the leech Hirudo medicinalis
N. Morel, M. Israel, M. Synguelakis and G. Le Gal la Salle
169
Identification of two proteolipid antigens with different localization at Torpedo neuromuscular synapses
Paul Madtes Jr, Geoffry Fuller and Kathleen Gregg
179
Sensitivity of GABA-displaceable [3H]muscimot binding depends upon the composition of the buffering medium
Christina M. Hall and Jan-Olof Karlsson
185 Aleuria lectin remains bound to its receptors during rapid axonal transport in retinal ganglion cells
Rosemary J. Wilkinson and David G. Nicholls
191
Compartmentation of glutamate and aspartate within cerebral cortical synaptosomes: evidence for a non-cytoplasmic origin for the calciumreleasable pool of glutamate
S. J. Taylor, J. Haggblad and S. A. Greenfield
199
Measurement of cholinesterase activity released from the brain "on-line" and in vivo
A. Garzon-Aburbeh, A. W. Lipkowski, D. L. Larson and P. S. Portoghese
207
Transfer of fatty acyl groups from membrane phosphatides to opiate ligands
C. Charriere-Bertrand, G. le Prince, C. Bouchier, C. Fages, M. Tardy and J. Nunez
215
Expression of tubulin, GFAP and of their encoding mRNAs during the proliferation and differentiation of cultured astrocytes
Alessandro Poli, Ottavio Gandolfi, Paola Roncada, Tiziana Guarnieri, Roberta Lucchi and Luigi Villani
223
Reversible effects of 1-methyl-4-phenylpyridinium dopaminergic neurons in goldfish retina
T. J. Montine and T. L. Sourkes
227
Behaviour of ~-methylserotonin in rat brain synaptosomes
R. J. Huxtable, S. Crosswell and D. Parker
233
Phospholipid composition and taurine content of synaptosomes in developing rat brain
Protein kinase C-mediated inhibition of excitatory amino acidstimulated phosphoinositide hydrolysis in the neonatal rat hippocampus binding
ion (MPP +) on
Index
v
Ambrish J. Patel, Anthony Hunt and Jozsef Kiss
239 Neonatal thyroid deficiency has differential effects on cell specific markers for astrocytes and oligodendrocytes in the rat brain
Masako Hagihara, Kennichiro Fujishiro, Akira Takahashi, Makoto Naoi and Toshiharu Nagatsu
249 A Rapid Publication: Cyclosporin A, an immune suppressor, enhanced neurotoxicity of N-methyl-4-phenyl-l,2,3,6-tetrahydropyridine (MPTP) to mice 255 News Items
Number 3 257 Editorial Anna Starzec, Mohieddine Moumni, Gisdle D'Angelo-Bernard, Yannick Lerrant, Marian Jutisz and Raymond Counis
259 Cyclic AMP enhances gene expression, synthesis and release of newly synthesized alpha and luteinizing hormone beta subunits in cultured rat anterior pituitary cells
Chen Chen, Jin Zhang, Govindan Dayanithi, Jean-Didier Vincent and Jean-Marc Israel
265 Cationic currents on identified rat gonadotroph cells maintained in primary culture
B. Sion, E. Saint Dizier, J. Duval and M. L. Thieulant
277
Steroid receptors and regulation of LH and secretogranin II (GP87) secretion in pituitary cell aggregates
Bernardo Pensa, Marco Achilli, Mario Fontana, Anna Maria Caccuri and Doriano Cavallini
285
S-Aminoethyl-L-cysteine transaminase from bovine brain: purification to homogeneity and assay of activity in different regions of the brain
Marshall K. Cheung
293 The specificity of glutamate inhibition of protein synthesis in synaptosomal fractions from rat cerebral cortex
Marika Eller and Jaak J/irv
301
A. Kenessey, M. Banay-Schwartz, T. DeGuzman and A. Lajtha
307 Regional distribution of brain calpastatin and of calpain II. Activity with casein and with endogenous brain protein substrates
Makoto Naoi, Tsutomu Takahashi, Hasan Parvez, Ryosuke Kabeya, Eiich Taguchi, Keiko Yamaguchi, Yoko Hirata, Masayasu Minami and Toshiharu Nagatsu
315
N-Methylisoquinolinium ion as an inhibitor of tyrosine hydroxylas¢, aromatic L-amino acid decarboxylase and monoamine oxidase
Georges Vauquelin, Jacques De Keyser, Banyingela Kanyinda and Maurice Vanhaelen
321
(+)Tetrahydroanisocycline and (+)tetrahydropalmatine binding to D1 and D2 dopaminergic receptors in human putamen
N. A. Sharif, J. L. Nunes, A. D. Michel and R. L. Whiting
325 Comparative properties of the dopamine transport complex in dog and rodent brain: striatal [3H]GBR12935 binding and [3H]dopamine uptake
C. Moret, I. Pastrie and M. Briley
333
Phillip J. Robinson, Donald R. Gehlert, Enrico Sanna and Ingeborg Hanbauer
339 Two fractions enriched for striatal synaptosomes isolated by percoll gradient centrifugation: synaptosome morphology, dopamine and serotonin receptor distribution, and adenylate cyclase activity
Rainer Schwitzkowsky and Lfiszl6 Hetey
349 Characterization of synaptosomal dopamine release in rat and human brain after post-mortem storage and cryopreservation
M. K. Gaitonde and Elizabeth Murray
355 The effect of conditions of homogenization on the activity of pyruvate dehydrogenase and its stability in brain homogenates
Kinetics of N-methylscopolamine interaction with muscarinic receptor from rat cerebral cortex
Effects of scopolamine treatment and lesion of the nucleus basalis upon various cholinergic markers in the rat brain cortex
Index
vi Yoshiyuki Ohmori and Kinya Kuriyama
359
Negative coupling of ~,-aminobutyric acid (GABA)B receptor with phosphatidylinositol turnover in the brain
A. J. Cholewinski, J. C. Reid, A. M. McDermott and G. P. Wilkin
365
Purification of astroglial-cell cultures from rat spinal cord: the use of D-valine to inhibit fibroblast growth
371
Book Reviews
375
News Items
Claudia Martini, Rossella Pacini, Gino Giannaccini and Antonio Lucacchini
377
[3sS]TBPS binding to purified benzodiazepine~GABA ionophore receptor complex: the effect of GABA on the modulation exerted by benzodiazepine site ligands
Lois Winsky, Hiroyasu Nakata and David M. Jacobowitz
381
Identification of a calcium binding protein highly localized to the cochlear nucleus
S. C. R. Lummis and D. B. Sattelle
391
Insect nervous system [3H]saxitoxin binding sites: characterization and target size
Giuseppe Arienti, Giuseppe Fratto, Gian Luigi Piccinin, Maria Teresa Ramacci, Licia Pacifici, Mariangela Rossi and Lanfranco Corazzi
397
Valproic acid and bicuculline affect the formation of glycerolipid in rat brain
Andrzej Szutowicz, Hanna Bielarczyk, Danuta Sosnowska and Barbara Ciszek
403
Regulation of citrate metabolism and acetylcholine synthesis by Ca 2+ in rat brain synaptosomes
M. Thereza R. Perez and Berndt Ehinger
411
Multiple neurotransmitter systems influence the release of adenosine derivatives from the rabbit retina
Junya Tanaka, Kunitoshi Tada, Masatoshi Takeda, Shiro Hariguchi and Tsuyoshi Nishimura
421
Effect of metallic cations and pH on reassembly of glial fibrillary acidic protein
P. C. Hopkins, I. S. Kay and W. E. Davies
429
A rapid method for the determination of taurine in biological tissue
R. Grimaldi, C. G. Eriksson, P. Eneroth, L. F. Agnati and K. Fuxe
433
Evidence for nuclear ornithine decarboxylase activity in different brain regions of the male rat
H~16ne Fournier and Roger F. Butterworth
439
Effects of maternal thiamine deficiency on the development of thiamine-dependent enzymes in regions of the rat brain
H. Lara and J. Belmar
445
Biochemical evidence for the presence of small and large noradrenergic storage vesicles isolated from cat ovary in isoosmotic conditions. Distribution of dopamine-/~-hydroxylase activity
Riccardo Ghidoni, Amelia Fiorilli, Marco Trinchera, Bruno Venerando, Vanna Chigorno and Guido Tettamanti
455
Uptake, cell penetration and metabolic processing of exogenously administered GM 1 ganglioside in rat brain
ltaru Toyoshima, Akio Yamamoto, Osamu Masamune, Shoji Yamada and Mei Satake
467
Difference in phosphorylation of neurofilament proteins in motor neurons and spinal ganglion cells
Bernadette Earley, Anat Biegon and B. E. Leonard
475
Quantitative autoradiographic analysis of muscarinic receptors and quantitative histochemistry of acetylcholinesterase in the rat brain after trimethyltin intoxication
Gary A. Walter and John W. Phillis
485
5-Aminoimidazole-4-carboxamide riboside administration and purine release from the hypoxic/hypotensive rat cerebral cortex
Number 4
Index
vii
Rie Miyoshi, Shozo Kito, Hajime Ishida and Mika Nakashima
493
Modulation of dopamine DI receptor binding by neurotensin in the rat striatum
Masazumi Takeshita, Satoshi Yoshida and Toshitsugu Yubisui
497
Concomitant decrease in the elongation and condensation activities of very-long chain fatty acyl-CoA in jimpy mouse
Q. Pei, T. Zetterstr6m and M. Fillenz
503
Measurement of extracellular 5-HT and 5-HIAA in hippocampus of freely moving rats using microdialysis: long-term applications
A. Szab6, J. Nemcs6k, P. K~sa and K. Gulya
511
Muscarinic cholinergic components in the carp brain
Philippe Mailly, Amena Ben Youn6s-Chennoufi and Suzanne Bon
517
The monoclonal antibodies Elec-39, HNK-I and NC-I recognize common structures in the nervous system and muscles of vertebrates
D. Maysinger, B. Zorc, B. R. Leavitt, I. Butula, F. L. Chubb and A. C. Cuello
531
Structural analogs of hemicholinium: effects on cholinergic and GABAergic markers in the CNS
Jeffrey H. Boatright and P. Michael luvone
541
GABA and the regulation of serotonin N-acetyltransferasc activity in amphibian retina--I. Effects of GABA agonists and antagonists
Jeffrey H. Boatright and P. Michael Iuvone
549
GABA and the regulation of serotonin N-acetyltransferase activity in amphibian retina--II. The role of dopamine
Toshikuni Sasaoka, Norio Kaneda, Yoshikazu Kurosawa, Keisuke Fujita and Toshiharu Nagatsu
555
A Rapid Publication: Structure of human phenylethanolamine Nmethyltransferase gene: existence of two types of mRNA with different transcription initiation sites
Jerzy Z. Nowak and Ewa Zurawska
567
A Rapid Publication: Serotonin N-acetyltransferase (NAT) activity in hen retina and pineal gland: in vivo pharmacological induction at noon and antagonism of the light-evoked suppression at night
575
Book Review
577
News Items
N.C.I. 16/1--1
AUTHOR INDEX Achilli M. 285 Agnati L. F. 107, 433 Almqvist P. 73 Altsch/iller N. 97 Annaert W. 39 Arienti G. 397 Banay-Schwartz M. 307 Barat A. 115 Benfenati F. 107 Belmar J. 445 Biegon A. 475 Bielarczyk H. 403 Boatright J. H. 541, 549 Boiron F. 61 Bon S. 517 Bouchier C. 215 Briley M. 333 Brunelli M. 161 Budai D. 153 Butterworth R. F. 439 Butula I. 531 Caccuri A. M. 285 de Carvalho L. P. 9 Cassagne C. 61 Cattani M. 161 Cavallini D. 285 Charriere-Bertrand C. 215 Chen Chen 265 Cheung M. K. 293 Chigomo V. 455 Cholewinski A. J. 365 Chubb F. L. 531 Cipollini G. 161 Ciszek B. 403 Cohen G. 127 Corazzi L. 397 Counis R. 259 Crosswell S. 233 Cuello A. C. 531 D'Angelo-Bernard G. 259 Davies W. E. 429 Dawson R. M. 49 Dayanithi G. 265 De Deyn P. P. 39 De Keyser J. 321 De Potter W. P. 39 DeGuzman T. 307 Deschamps C.-M. 145 D'Hooge R. 39 Doble A. 1 Dopico A. M. 97 Dunglison G. F. 91 Duval J. 277 Earley B. 475
Ehinger B. 411 Eller M. 301 Eneroth P. 433 Eriksson C. G. 433 Evans J. M. 127 Fages C. 215 Fillenz M. 503 Fiorilli A. 455 Fontana M. 285 Fournier H. 439 Fowler C. J. 73 Fratto G. 397 Fujishiro K. 249 Fujita K. 555 Fuller G. 179 Fuxe K. 107, 433 Gaitonde M. K. 355 Gandolfi O. 223 Garcia-Gil M. 161 Garzon-Aburbeh A. 207 Gehlert D. R. 339 Ghidoni R. 455 Giannaccini A. 377 Gray P. J. 49 Greenfield S. A. 199 Gregg K. 179 Grimaldi R. 433 Guarnieri T. 223 Gulya K. 153, 511 Haggblad J. 199 Hagihara M. 249 Hall C. M. 185 Hanbauer I. 339 Hariguchi S. 421 Heape A. 61 Hetey L. 349 Hirata Y. 315 Hirouchi M. 33 Hopkins P. C. 429 Hunt A. 239 Huxtable R. J. 233 Ishida H. 493 Israel J.-M. 265 Israel M. 169 Iuvone P. M. 541, 549 Jacobowitz D. M. 381 Jaim-Etcheverry G. 97 J/irv J. 301 Jin Zhang 265 Jutisz M. 259 Kabeya R. 315 Kaneda N. 555 ix
Kanyinda B. 321 Karlsson J.-O. 185 K~isa P. 153, 157, 511 Katagiri T. 33 Kato T. 55 Kay I. S. 429 Kenessey A. 307 Kiss J. 239 Kito S. 493 Kouda T. 17 Kuriyama K. 33, 359 Kurosawa Y. 555 Kuwano R. 33 Lajtha A. 307 Lambolez B. 145 Lara H. 445 Larson D. L. 207 Leavitt B. R. 531 Lee H. S. 25 Le Gal la Salle G. 169 Leonard B. E. 475 Lerrant Y. 259 Lipkowski A. W. 207 L6pez J. J. $7 Lucacchini A. 377 Lucchi R. 223 Lummis S. C. R. 391 Madtes P. Jr 179 Mailly P. 517 Martini C. 377 Masamune O. 467 Mayo J. 97 Maysinger D. 531 McDermott A. M. 365 Meguri H. 17 Merlo Pich E. 107 Michaelson S. 49 Michel A. D. 325 Minami M. 315 Miyoshi R. 493 Montine T. J. 227 Morel N. 169 Moret C. 333 Moumni M. 259 Murray E. 355 Nagatsu T. 249, 315, 555 Nakashima M. 493 Nakata H. 381 Naoi M. 249, 315 Nemcs6k J. 511 Nicholls D. G. 191 Nilsson S. 73 Nishimura T. 421 Nowak J. Z. 567 Nunes J. L. 325
x Nunez J. 215 Ogita K. 17, 137 Ohgaki T. 17 Ohmori Y. 359 O'Neill C. 73 Pacifici L. 397 Pacini R. 377 Parker D. 233 Parvez H. 315 Pastrie I. 333 Patel A. J. 239 Pei Q. 503 Pensa B. 285 Perez M. T. R. 411 Perrier M. L. I Phillis J. W. 485 Piccinin G. L. 397 Pickut B. A. 39 Poli A. 223 Portoghese P. S. 207 le Prince G. 215
Index Sasaoka T. 555 Satake M. 467 Sattelle D. B. 391 Schoepp D. D. 131 Schwitzkowsky R. 349 Shanley B. C. 91 Sharif N. A. 325 Sion B. 277 Sosnowska D. 403 Sourkes T. L. 227 Starzec A. 259 Synguelakis M. 169 Szab6 A. 51 l Szutowicz A. 403
Rakonczay Z. 157 Ramacci M. T. 397 Ramirez G. 115 Reid J. C. 365 Robinson P. J. 339 Roncada P. 223 Rosario P. 115 Rossi M. 397 Rossier J. 145 Ruggeri M. 107
Tada K. 421 Taguchi E. 315 Takahashi A. 249 Takahashi T. 315 Takahashi Y. 33 Takeda K. 55 Takeda M. 421 Takeshita M. 497 Takita M. 55 Tan C. H. 25 Tanaka J. 421 Tardy M. 215 Taylor S. J. 199 Teo W. L. 25 Tettamanti G. 455 Thieulant M. L. 277 Tongiorgi E. 161 Toyoshima I. 467 Trinchera M. 455
Saint Dizier E. 277 Sanna E. 339
Uchida S. 17 Uchiumi F. 55
Ungerstedt U. 107 Upsher C. M. 49 Vanhaelen M. 321 Vauquelin G. 321 Venerando B. 455 Verzwijvelen A. 39 Villani L. 223 Vincent J.-D. 265 Volterra V. 107 Walter G. A. 485 Whiting R. L. 325 Wiehager B. 73 Wilce P. A. 91 Wilk E. K. 81 Wilk S. 81 Wilkin G. P. 365 Wilkinson R. J. 191 Winblad B. 73 Winsky L. 381 Wolff J. R. 157 Wong P. T.-H. 25 Yamada K. 17 Yamada S. 467 Yamaguchi K. 315 Y a m a m o t o A. 467 Yoneda Y. 17, 137 Yoshida S. 497 Younds-Chennoufi A. B. 517 Yubisui T. 497 Zetterstr6m T. 503 Zieher L. M. 97 Zini 1. 107 Zorc B. 531 Zurawska E. 567
SUBJECT INDEX Acetylcholinesterase - in c a r p b r a i n , 511 Acetylcholine - in c a r p brain, 511 Acetylcholine release, 9 Acetylcholine release - modulation by muscarinic receptors, 9 Acetylcholine s y n t h e s i s - e f f e c t of c a l c i u m , 403 Acetylcholine s y n t h e s i s - in s y n a p t o s o m e s , 403 Acetylcholinesterase - a l l o s t e r i c p r o p e r t i e s , 49 Acetylcholinesterase characterisation of Triton solubilised form, 49 Acetylcholinesterase - e f f e c t of NaBr, 157 Acetylcholinesterase - e f f e c t of t r i m e t h y l t i n i n t o x i c a t i o n , 475 Acetylcholinesterase - histochemistry, 475 Acetylcholinesterase - in s u p e r i o r c e r v i c a l g a n g l i o n , 157 Acetylcholinesterase - k i n e t i c p r o p e r t i e s , 49 Acetylcholinesterase - m o l e c u l a r forms, 157 Acetylcholinesterase - m o n o c l o n a l a n t i b o d i e s , 517 A d e n o s i n e d e r i v a t i v e s - r e l e a s e , 411 A d e n y l a t e c y c l a s e a c t i v i t y - in s y n a p t o s o m e s , 339 A l e u r i a l e c t i n - b i n d s to r e c e p t o r s , 185 5-aminoimidazole-4-carboxamide riboside - effect on purine r e l e a s e , 485 S-aminoethyl-L-cysteine transaminase purification and characterisation, 285 A n t i b o d i e s - to p r o t e o l i p i d s , 169 Aromatic-L-amino acid decarboxylase inhibited by Nmethyliosolinuim, 315 A s t r o c y t e c u l t u r e s - e x p r e s s i o n of m R N A s , 215 A s t r o c y t e s - e f f e c t of t h y r o i d d e f i c i e n c y on cell, 239 A s t r o g l i a l cell c u l t u r e s - f r o m s p i n a l cord, 365 Autoradiography - of m u s c a r i n i c r e c e p t o r s , 91, 475 A x o n a l t r a n s p o r t - in r e t i n a l g a n g l i o n cells, 185 A x o n a l t r a n s p o r t - Of A l e u r i a l e c t i n r e c e p t o r s , 185 A x o n a l t r a n s p o r t - of n o r a d r e n a l i n e , dopamine-hydroxylase and NPY, 39 A x o n a l t r a n s p o r t - of r e c e p t o r s , 185 Benzodiazepine c o m p l e x - b i n d i n g of ( 3 s S ) T B P S , Benzodiazepine r e c e p t o r , 145 Benzodiazepines - interaction with a histadine Bicuculline - e f f e c t on g l y c e r o l i p i d , 397 B i n d i n g - of 3 H - G A B A , 115 B i n d i n g - of a H - m u s c i m o l , 179 B i n d i n g - of 3 H - t r y p t o p h a n , 25
377 residue,
C - A M P - e n h a n c e s g e n e e x p r e s s i o n , 259 C-AMP dependent phosphorylation, 161 C - D N A c l o n i n g - of G A B A a r e c e p t o r , 33 C a l c i u m - e f f e c t on a c e t y l c h o l i n e m e t a b o l i s m , 403 C a l c i u m - e f f e c t on c i t r a t e m e t a b o l i s m , 403 C a l c i u m b i n d i n g p r o t e i n , 381 C a l m o d u l i n - e f f e c t of 3 H - g l u t a m a t e a c c u m u l a t i o n , 17 C a l m o d u l i n - e f f e c t on 3 H - g l u t a m a t e b i n d i n g , 17 C a l p a i n II - a c t i v i t y w i t h c a s e i n , 307 C a l p a i n II - r e g i o n a l d i s t r i b u t i o n , 307 C a l p a s t a t i n - a c t i v i t y in p r e s e n c e of casein, 307 Calpastatin - regional distribution, 307 ~-carbolines - interaction with benzodiazepine receptor, C a r p b r a i n - m u s c a r i n i c system, 511 C a s e i n - e f f e c t on c a l p a i n II a c t i v i t y , 307 C a s e i n - e f f e c t on c a l p a s t a t i n a c t i v i t y , 307 Catecholamine l e v e l s - e f f e c t of x - i r r a d i a t i o n , 97 C a t i o n i c c u r r e n t s - of g o n a d o t r o p h cells, 265 C a t i o n s - e f f e c t on GFAP, 421 3 H - C D - b i n d i n g to m u s c a r i n i c r e c e p t o r s , 333 Cholecystokinin o c t o p e p t i d e s u l f a t e - i m m u n o a s s a y , 55 Choline acetyltransferase - in c a r p brain, 511 xi
145
145
xii
Index
C h o l i n e r g i c m a r k e r s - e f f e c t of h e m i c h o l i n i u m analogs, 531 C h o l i n e s t e r a s e - release, 199 Cholinesterase activity - measurement, 199 3H-(+)-cis-methyldioxolane - see sH-CD, 333 C i t r a t e m e t a b o l i s m - e f f e c t of calcium, 403 C i t r a t e m e t a b o l i s m - in s y n a p t o s o m e s , 403 C l o n i n g - of h u m a n G A B A a r e c e p t o r , 33 C o c h l e a r n u c l e u s - l o c a l i s a t i o n of c a l c i u m b i n d i n g , 381 Cryopreservation - d o p a m i n e r e l e a s e , 349 2',3'-cyclic nucleotide 3'phosphohydrolase - in g l i a l cells, C y c l o s p o r i n A - e n h a n c e s n e u r o t o x i c i t y of MPTP, 249
239
D - v a l i n e - i n h i b i t s f i b r o b l a s t g r o w t h , 365 D1 r e c e p t o r s - b i n d i n g studies, 321 D2 r e c e p t o r s - b i n d i n g studies, 321 D o p a m i n e - a c t i o n on s e r o t o n i n - N - a c e t y l t r a n s f e r a s e , 549 D o p a m i n e b e h a v i o u r s , 107 D o p a m i n e c o n t e n t - e f f e c t of x - i r r a d i a t i o n , 97 D o p a m i n e n e u r o n e s - e f f e c t of n e u r o t o x i n s , 127 D o p a m i n e r e c e p t o r s - on s y n a p t o s o m e s , 339 D o p a m i n e r e l e a s e - e f f e c t of u r i d i n e , 107 D o p a m i n e r e l e a s e - f r o m s t r i a t a l slices, 107 Dopamine release - from synaptosomes, 349 D o p a m i n e u p t a k e sites - b i n d i n g of 3 H - G B R 12935, 325 Dopamine-~-hydoxylase - a x o n a l t r a n s p o r t , 39 Dopamine-~-hydoxylase - subcellular distribution, 39 Dopamine-~-hydroxylase a c t i v i t y - in v e s i c l e s , 445 D o p a m i n e r g i c n e u r o n e s - e f f e c t of MPP+, 223 E l e c - 3 9 - m o n o c l o n a l a n t i b o d y , 517 E t h a n o l - e f f e c t on m u s c a r i n i c r e c e p t o r s , 91 E x c i t a t o r y a m i n o a c i d r e c e p t o r s - a n d p r o t e i n k i n a s e C, 131 E x c i t a t o r y a m i n o acids, 1 Excitatory amino acids - phosphoinositide h y d o l y s i s , 131 E x c i t a t o r y a m i n o a c i d s - r e c e p t o r s l i n k e d to i n o s i t o l p h o s p h a t e s , Excitatory amino acids - receptors, 1 E x p r e s s i o n of G F A P mRNAs, 215 E x p r e s s i o n of t u b u l i n mRNAs, 215 F a t t y acyl g r o u p s - f r o m p h o s p h a t i d e s to o p i a t e ligands, F a t t y a c y l - C o A - e l o n g a t i o n a n d c o n d e n s a t i o n , 497 F a t t y a c y l - C o A - in j i m p y m o u s e , 497 F i b r o b l a s t g r o w t h - i n h i b i t e d b y D - v a l i n e , 365
207
3 H - G A B A b i n d i n g - in D r o s o p h i l a CNS m e m b r a n e s , 115 GABA regulates serotonin-N-acetyltransferase, 549 GABA r e g u l a t i o n of s e r o t o n i n - N - a c e t y l t r a n s f e r a s e , 541 G A B A d i s p l a c e a b l e S H - m u s c i m o l b i n d i n g , 179 G A B A a r e c e p t o r - c l o n i n g of c-DNA, 33 GABAb receptors - negative coupling with phosphatidylinositol t u r n o v e r , 359 G a n g l i o s i d e - uptake, 455 3 H - G B R 12935 b i n d i n g - to d o p a m i n e u p t a k e sites, 325 Sene e x p r e s s i o n - e f f e c t of c-AMP, 259 G e n e s t r u c t u r e - of p h e n y l e t h a n o l a m i n e - N - m e t h y l t r a s f e r a s e , 555 G F A P - e f f e c t of m e t a b o l i c c a t i o n s , 421 GFAP e f f e c t of pH, 421 G F A P mRNAs, 215 G l i a l f i b r i l l a r y a c i d p r o t e i n - see GFAP, 421 3 H - g l u t a m a t e - a c c u m u l a t i o n a n d b i n d i n g , 17 3 H - g l u t a m a t e a c c u m u l a t i o n - e f f e c t of c a l m o d u l i n , 17 3 H - g l u t a m a t e b i n d i n g - f r o m rat a d r e n a l , 137 3 H - g l u t a m a t e b i n d i n g - q u i s q u a l a t e s e n s i t i v e , 137 3 H - g l u t a m a t e u p t a k e - e f f e c t of c a l m o d u l i n , 17 G l u t a m a t e - i n h i b i t s p r o t e i n s y n t h e s i s , 293 G l u t a m i n e s y n t h e t a s e - in g l i a l cells, 239 -
-
-
1
Index
xiii
G l y c e r o l i p i d - e f f e c t of b i c u c u l l i n e , 3~-7 G l y c e r o l i p i d - e f f e c t of v a l p r o i c acid, 397 G l y c e r o l i p i d - f o r m a t i o n , 397 GMI g a n g l i o s i d e - u p t a k e , 455 G o n a d o t r o p h c e l l s - c a t i o n i c c u r r e n t s , 265 G o n a d o t r o p h c e l l s - in c u l t u r e , 265 H a l o p e r i d o l t r e a t m e n t - u r i d i n e e f f e c t s on b e h a v i o u r , 107 Hemicholinium a n a l o g s - e f f e c t on c h o l i n e r g i c a n d a n d GABAergic systems, 531 H i s t i d i n e r e s i d u e - of B e n z o d i a z e p i n e r e c e p t o r , 145 H N K - I - m o n o c l o n a l a n t i b o d y , 517 H P L C - f o r d e t e r m i n i n g t a u r i n e , 429 5-HT - a n a l y s i s b y m i c r o d i a l y s i s , 503 5-HT - in f r e e l y m o v i n g rats, 503 5-hydroxyindoleacetic acid - analysis by microdialysis, 503 5-hydroxyindoleacetic a c i d - in f r e e l y m o v i n g rats, 503 6-hydroxydopamine - e f f e c t on d o p a m i n e n e u r o n e s , 127 6-hydroxydopamine - n e u r o t o x i n , 127 Hypoxic/hyptensive rats - r e l e a s e of p u r i n e s , 485 I m m u n o a s s a y - Of c h o l e c y s t o k i n i n , 55 I n o s i t o l p h o s p h a t e - in n e o n a t a l rat s t r i a t u m , 1 I n o s i t o l p h o s p h a t e - r e c e p t o r s of e x c i t a t o r y a m i n o acids, 1 Inositol phosphates - receptors, 1 I n o s i t o l p h o s p h o l i p i d b r e a k d o w n - in S H - S Y S Y cells, 73 I n s e c t n e r v o u s s y s t e m - b i n d i n g of 3 H - s a x i t o x i n , 391 Jimpy
mouse
- fatty
acyl-CoA,
497
Luteinizing Luteinizing
hormone hormone
- r e g u l a t i o n of s t e r o i d r e c e p t o r s , - s y n t h e s i s of s u b u n i t s , 259
277
MAO -inhibited by N-methylisoquinolinium ion, 315 Methylserotonin - in s y n a p t o s o m e s , 227 l-methyl-4-phenylpyridiniu~ ion [MPP+] - e f f e c t on dopaminergic n e u r o n e s in g o l d f i s h retina, 223 N-methyl-4,phenyl-l,2,3,6-tetrahydropyridine (MPTP) - see, 249 N-methylisoquinolinium ion - i n h i b i t o r of a r o m a t i c - L - a m i n o acid decarboxylase, 315 N-methylisoquinolinium ion - i n h i b i t o r of MA0, 315 N-methylisoquinolinium ion - i n h i b i t o r of t y r o s i n e - h y d r o x y l a s e , 315 N-methylscopolamine - b i n d i n g , 301 N-methylscopolamine k i n e t i c s of i n t e r a c t i o n with muscarinic r e c e p t o r s , 301 M o d u l a t i o n - of a c e t y l c h o l i n e release, 9 Monoaminergic l e v e l s - e f f e c t of M P P + in retina, 223 M o n o c l o n a l a n t i b o d i e s - to a c e t y l c h o l i n e s t e r a s e , 517 MPP+ e f f e c t on m o n o a m i n e l e v e l s in g o l d f i s h retina, 223 MPTP neurotoxicity - e n h a n c e d b y c y c l o s p o r i n A, 249 MRNA of p h e n y l e t h a n o l a m i n e - N - m e t h y l t r a n s f e r a s e , 555 MRNAs f r o m t u b u l i n a n d G F A P in a s t r o c y t e s , 215 M u s c a r i n i c r e c e p t o r s - e f f e c t of e t h a n o l , 91 M u s c a r i n i c a n t a g o n i s t s - e f f e c t on a u t o r e c e p t o r s , 153 Muscarinic autoreceptors, 153 Muscarinic autoreceptors - e f f e c t of a n t a g o n i s t s , 153 M u s c a r i n i c c o m p o n e n t s - in c a r p brain, 511 Muscarinic receptors, 9 Muscarinic receptors - autoradiography, 91 M u s c a r i n i c r e c e p t o r s - b i n d i n g of 3 H - Q N B a n d 3H-CD, 333 M u s c a r i n i c r e c e p t o r s - c o u p l e d to i n o s i t o l p h o s p h a t e s , 73 M u s c a r i n i c r e c e p t o r s - do not s e n s i t i z e , 9 M u s c a r i n i c r e c e p t o r s - e f f e c t of s c o p o l a m i n e t r e a t m e n t , 333 M u s c a r i n i c r e c e p t o r s - e f f e c t of t r i m e t h y l tin i n t o x i c a t i o n , 475 Muscarinic receptors - interaction with N-methylscopolamine, 301 Muscarinic receptors - modulates acetylcholine release, 9 Muscarinic receptors - quantitative autoradiography, 475 S H - m u s c i m o l b i n d i n g - s e n s i t i v i t y to GABA, 179 -
-
-
xiv
Index N a B r t r e a t m e n t - e f f e c t of a c e t y l c h o l i n e s t e r a s e , 157 NC-I - monoclonal-antibody, 517 Neurofilament proteins - phosphorylation, 467 N e u r o f i l a m e n t p r o t e i n s - i n n e u r o n e s , 467 N e u r o p e p t i d e Y - s u b c e l l u l a r d i s t r i b u t i o n , 39 N e u r o t o x i n s - e f f e c t o n d o p a m i n e n e u r o n e s , 127 N o r a d r e n a l i n e - a x o n a l t r a n s p o r t , 39 N o r a d r e n a l i n e - s u b c e l l u l a r d i s t r i b u t i o n , 39 N o r a d r e n a l i n e c o n t e n t - e f f e c t of x - i r r a d i a t i o n , 97 N o r a d r e n e r g i c s t o r a g e v e s i c l e s , 445 N u c l e o t i d e s e q u e n c e s - of G A B A a r e c e p t o r a - s u b u n i t , 33 O l i g o d e n d r o c y t e s - e f f e c t of t h y r o i d d e f i c i e n c y o n c e l l m a r k e r s , 239 " O n - l i n e " - m e a s u r e of c h o l i n e s t e r a s e a c t i v i t y r e l e a s e , 199 O p i a t e l i g a n d s - t r a n s f e r of f a t t y a c y l g r o u p s f r o m p h o s p h a t e s , 207 O r n i t h i n e d e c a r b o x y l a s e a c t i v i t y , 433 O r n i t h i n e d e c a r b o x y l a s e a c t i v i t y - s u b c e l l u l a r d i s t r i b u t i o n , 433 P a l m i t a t e - in n o r m a l a n d t r e m b l e r m i c e , 61 P a l m i t a t e - u p t a k e a n d m e t a b o l i s m , 61 P a t c h - c l a m p - of g o n a d o t r o p h s , 265 Phenylethanolamine-N-methyltransferase g e n e - m R N A , 555 Phenylethanolamine-N-methyltransferase g e n e - s t r u c t u r e , 555 P h o s p h a t i d e s - t r a n s f e r of f a t t y a c y l g r o u p s to o p i a t e l i g a n d s , 207 Phosphatidylinositol turnover - negatively coupled with GABAb r e c e p t o r s , 359 P h o s p h o i n o s i t i d e h y d r o l y s i s - e f f e c t of e x c i t a t o r y a m i n o acids, 131 P h o s p h o r y l a t i o n - of n e u r o f i l a m e n t p r o t e i n s , 467 P h o s p h o r y l a t i o n - c - A M P d e p e n d e n t p r o c e s s , 161 P h o s p h o r y l a t i o n - in l e e c h CNS, 161 P h o s p h o r y l a t i o n - of 79 k D a p r o t e i n , 161 P i t u i t a r y c e l l a g g r e g a t e s , 277 P i t u i t a r y c e l l s - in t i s s u e c u l t u r e , 259 P r o t e i n k i n a s e C - a n d n e o n a t a l e x c i t a t o r y a m i n o a c i d s , 131 P r o t e i n s y n t h e s i s - i n h i b i t e d b y g l u t a m a t e , 293 P r o t e o l i p i d a n t i g e n s - at T o r p e d o n e u r o m u s c u l a r s y n a p s e s , 169 Proteolipids - immunohistochemical l o c a l i s a t i o n , 169 Purine release effect of 5-aminoimidazole-4-carboxamide r i b o s i d e , 485 Purine release - from hypoxic/hypotensive r a t c o r t e x , 485 Pyroglutamyl peptidase II a thyrotropin release hormone d e g r a d i n g e n z y m e , 81 P y r o g l u t a m y l p e p t i d a s e II - p r o p e r t i e s , 81 P y r u v a t e d e h y d r o g e n a s e - a c t i v i t y , 355 3H-(-)-quinuclidinyl Quisqualate - effect
b e n z i l a t e - s e e 3 H - Q N B , 333 on 3 H - g l u t a m a t e b i n d i n g , 137
R e c e p t o r s - a n d a x o n a l t r a n s p o r t , 185 R e c e p t o r s - f o r s t e r o i d s , 277 Receptors - to excitatory amino acids, 1 R e l e a s e - of a c e t y l c h o l i n e , 9 R e l e a s e - of a d e n o s i n e d e r i v a t i v e s , 4 1 1 R e t i n a - d o p a m i n e r g i c n e u r o n e s , 223 R e t i n a - r e l e a s e of a d e n o s i n e d e r i v a t i v e s , 4 1 1 Retina - serotonin-N-acetyltransferase, 541 3 H - s a x i t o x i n - b i n d i n g sites, 391 3 H - s a x i t o x i n - b i n d i n g to s o d i u m c h a n n e l , 391 S c o p o l a m i n e - c h r o n i c e f f e c t o n m u s c a r i n i c r e c e p t o r s , 333 S e c r e t o g r a n i n II - a g o n a d o t r o p h p o l y p e p t i d e , 277 S e c r e t o g r a n i n II - r e g u l a t e d b y s t e r o i d r e c e p t o r s , 277 S e r o t o n i n r e c e p t o r s - o n s y n a p t o s o m e s , 339 Serotonin-N-acetyltransferase - in r e t i n a , 541, 549 Serotonin-N-acetyltransferase - r e g u l a t e d b y GABA, 541, 549 S H - S Y S Y n e u r o b l a s t o m a c e l l s - m u s c a r i n i c r e c e p t o r s , 73 S o d i u m c h a n n e l s - b i n d i n g of 3 H - s a x i t o x i n , 391
Index
xv
S t e r o i d r e c e p t o r s , 277 S t e r o i d r e c e p t o r s - r e g u l a t e l u t e i n i z i n g h o r m o n e , 277 Steroid receptors - regulate secretogranin II, 277 S y n a p t o s o m a l d o p a m i n e r e l e a s e - f r o m c r y o p r e s e r v e d tissue, 349 S y n a p t o s o m a l d o p a m i n e r e l e a s e - f r o m p o s t m o r t e m brain, 349 Synaptosomes - acetylcholine s y n t h e s i s , 403 S y n a p t o s o m e s - b e h a v i o u r of a - m e t h y l s e r o t o n i n , 227 S y n a p t o s o m e s - d o p a m i n e a n d s e r o t o n i n r e c e p t o r d i s t r i b u t i o n , 339 S y n a p t o s o m e s - d o p a m i n e r e l e a s e , 349 S y n a p t o s o m e s - f r o m rat c e r e b r a l cortex, 293 S y n a p t o s o m e s - m o r p h o l o g y in d i f f e r e n t f r a c t i o n s , 339 S y n a p t o s o m e s - p r o t e i n s y n t h e s i s , 293 S y n a p t o s o m e s - a d e n y l a t e c y c l a s e a c t i v i t y , 339 S y n a p t o s o m e s - in d i f f e r e n t f r a c t i o n s , 339 Taurine - determination, 429 (35S)t-butyl bicylophosphosphorothionate - see ( 3 5 S ) T B P S ( 3 s S ) T B P S - b i n d i n g to b e n z o d i a z e p i n e c o m p l e x , 377 (±)Tetrahydroanisocycline - b i n d i n g to D1 a n d D2 r e c e p t o r s , 321 (±)Tetrahydropalmatine - b i n d i n g to D1 a n d D2 r e c e p t o r s , 321 T h i a m i n e d e f i c i e n c y - e f f e c t on s p e c i f i c e n z y m e s , 439 T h i a m i n e d e p e n d e n t e n z y m e s , 439 T h y r o i d d e f i c i e n c y - a n d m a t u r a t i o n of g l i a l cells, 239 T h y r o i d d e f i c i e n c y - r e l a t e d to m a r k e r s for a s t r o c y t e s , 239 Thyrotropin release hormone degrading enzyme - pyroglutamyl p e p t i d a s e II, 81 Torpedo neuromuscular s y n a p s e s - p r o t e o l i p i d a n t i g e n , 169 T r e m b l e r m i c e - u p t a k e a n d m e t a b o l i s m of p a l m i t a t e , 61 T r i m e t h y l t i n i n t o x i c a t i o n - e f f e c t on m u s c a r i n i c r e c e p t o r s , 475 3 H - t r y p t o p h a n - b i n d i n g , 25 T u b u l i n m R N A s , 215 Tyrosine hydroxylase - inhibited by N-methylisoquinolinium ion, 315 U p t a k e - of p a l m i t a t e , 61 U r i d i n e - e f f e c t on d o p a m i n e r e l e a s e a n d b e h a v i o u r , 107 U r i d i n e e f f e c t s - f o l l o w i n g h a l o p e r i d o l t r e a t m e n t , 107 U r i d i n e t r e a t m e n t - h a l o p e r i d o l e f f e c t s on b e h a v i o u r , 107 Valproic Vesicles Vesicles Vesicles
a c i d - e f f e c t on g l y c e r o l i p i d , 397 - containing noradrenaline, 445 - dopamine-~-hydroxylase, 445 - f r o m cat ovary, 445
X-irradiation
- effect
on d o p a m i n e
and noradrenaline,
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NEUROCHEMISTRY INTERNATIONAL The Journal for the publication of cellular and molecular aspects of neurochemistry in the form of original and rapid research communications and also critical reviews and commentaries E x e c u t i v e Editors For U.K. Also for Reviews, Commentaries and Rapid Reports N. N. Osborne (Chairman): NuffieM Laboratory of Ophthalmology, University of Oxford, Walton Street, Oxford 0)(2 6,414I, U.K. For Europe and Africa: J. Rossier: CNRS Laboratoire de Physiologie Nerveuse, 91190 Gifs u r - Yvette, F r a n c e
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LIST OF CONTENTS VOLUME
15 ( 1 9 8 9 )
Number 1 A. Doble and M. L. Perrier
Pharmacology of excitatory amino acid receptors coupled to inositol phosphate metabolism in neonatal rat striatum
Lia Prado de Carvalho
Modulation of acetylcholine release in rat striatal slices by muscarinic receptors which do not desensitize
Yukio Yoneda, Kiyokazu Ogita, Kisa Yamada, Tomoko Kouda, Takao Ohgaki, Shuji Uchida and Haruo Meguri
17 High concentrations of calmodulin antagonists inhibit accumulation and binding activities of [3H]glutamate in rat brain
P. T.-H. Wong, H. S. Lee, C. H. Tan and W.L. Teo
25
Specific [3H]tryptophan binding sites in rat brain
Masaaki Hirouchi, Ryozo Kuwano, Takashi Katagiri, Yasuo Takahashi and Kinya Kuriyama
33
Nucleotide and deduced amino acid sequences of the GABA A receptor ~t-subunit from human brain
P. P. De Deyn, B. A. Pickut, A. Verzwijvelen, R. D'Hooge, W. Annaert and W. P. De Potter
39 Subcellular distribution and axonal transport of noradrenaline, dopamine-fl-hydroxylase and neuropeptide Y in dog splenic nerve
R. M. Dawson, P. J. Gray, C. M. Upsher and S. Michaelson
49
Katsumichi Takeda, Fumiaka Uchiumi, Masatoshi Takita and Takeshi Kato
55 A rapid enzyme immunoassay for cholectystokinin octapeptide sulfate
Anthony Heape, Fran¢oise Boiron and Claude Cassagne
61
High uptake and rapid metabolism of palmitate in peripheral nerves of normal and Trembler mice in vivo: similarities and differences
Christopher J. Fowler, Cora O'Neill, Per Almqvist, Sofie Nilsson, Birgitta Wiehager and Bengt Winblad
73
Muscarinic receptors coupled to inositol phospholipid breakdown in human SH-SY5Y neuroblastoma cells: effect of retinoic acid-induced differentiation
Sherwin Wilk and Elizabeth K. Wilk
81
Pyroglutamyl peptidase II, a thyrotropin releasing hormone degrading enzyme: purification and specificity studies of the rabbit brain enzyme
G. F. Dunglison, P. A. Wilce and B. C. Shanley
91
Autoradiographic studies on the effect of ethanol on muscarinic receptors in rat brain
Alejandro M. Dopico, Luis M. Zieher, Jos6 Mayo, Noe Altsehiiller, Juan J. L6pez and Guillermo Jaim-Etcheverry
97
Long-term changes in noradrenaline (NA) and dopamine (DA) contents of rat cerebellum following neonatal X-irradiation
L. F. Agnati, K. Fuxe, M. Ruggeri, E. Merlo Pith, F. Benfenati, V. Volterra, U. Ungerstedt and I. Zini
Modification of the kinetic properties of Triton-solubilized rabbit brain acetylcholinesterase by allosteric effectors at low ionic strength
107 Effects of chronic treatment with uridine on striatal dopamine release and dopamine related behaviours in the absence or the presence of chronic treatment with haloperidol iii
Index
iv
Paula Rosario, Ana Barat and Galo Ramirez
115 Characterization of binding sites for [3H]GABA in Drosophila melanogaster CNS membranes 121
Book Reviews
125
News Items
Number 2 Jacqueline M. Evans and Gerald Cohen
127 Commentary: Can trace amounts of neurotoxins destroy dopamine neurons?
Darryle D. Schoepp
131
Yukio Yoneda and Kiyokazu Ogita
137 Characterization of quisqualate-sensitive [3H]glutamate activity solubilized from rat adrenal
Bertrand Lambolez, Claude-Marguerite Deschamps and Jean Rossier
145
Interactions of benzodiazepines and /~-carbolines with a histidine residue of the benzodiazepine receptor
K. Gulya, D. Budai and P. K~isa
153
Muscarinic autoreceptors are differentially affected by selective muscarinic antagonists in rat hippocampus
Z. Rakonczay, P. K~sa and J. R. Wolff
157 Change in the distribution of acetylcholinesterase molecular forms in the rat superior cervical ganglion after NaBr treatment in t,it,o
M. Garcia-Gil, E. Tongiorgi, M. Cattani, G. Cipollini and M. Brunelli
161
cAMP-dependent protein phosphorylation of a 79 kDa protein in segmental ganglia of the leech Hirudo medicinalis
N. Morel, M. Israel, M. Synguelakis and G. Le Gal la Salle
169
Identification of two proteolipid antigens with different localization at Torpedo neuromuscular synapses
Paul Madtes Jr, Geoffry Fuller and Kathleen Gregg
179
Sensitivity of GABA-displaceable [3H]muscimot binding depends upon the composition of the buffering medium
Christina M. Hall and Jan-Olof Karlsson
185 Aleuria lectin remains bound to its receptors during rapid axonal transport in retinal ganglion cells
Rosemary J. Wilkinson and David G. Nicholls
191
Compartmentation of glutamate and aspartate within cerebral cortical synaptosomes: evidence for a non-cytoplasmic origin for the calciumreleasable pool of glutamate
S. J. Taylor, J. Haggblad and S. A. Greenfield
199
Measurement of cholinesterase activity released from the brain "on-line" and in vivo
A. Garzon-Aburbeh, A. W. Lipkowski, D. L. Larson and P. S. Portoghese
207
Transfer of fatty acyl groups from membrane phosphatides to opiate ligands
C. Charriere-Bertrand, G. le Prince, C. Bouchier, C. Fages, M. Tardy and J. Nunez
215
Expression of tubulin, GFAP and of their encoding mRNAs during the proliferation and differentiation of cultured astrocytes
Alessandro Poli, Ottavio Gandolfi, Paola Roncada, Tiziana Guarnieri, Roberta Lucchi and Luigi Villani
223
Reversible effects of 1-methyl-4-phenylpyridinium dopaminergic neurons in goldfish retina
T. J. Montine and T. L. Sourkes
227
Behaviour of ~-methylserotonin in rat brain synaptosomes
R. J. Huxtable, S. Crosswell and D. Parker
233
Phospholipid composition and taurine content of synaptosomes in developing rat brain
Protein kinase C-mediated inhibition of excitatory amino acidstimulated phosphoinositide hydrolysis in the neonatal rat hippocampus binding
ion (MPP +) on
Index
v
Ambrish J. Patel, Anthony Hunt and Jozsef Kiss
239 Neonatal thyroid deficiency has differential effects on cell specific markers for astrocytes and oligodendrocytes in the rat brain
Masako Hagihara, Kennichiro Fujishiro, Akira Takahashi, Makoto Naoi and Toshiharu Nagatsu
249 A Rapid Publication: Cyclosporin A, an immune suppressor, enhanced neurotoxicity of N-methyl-4-phenyl-l,2,3,6-tetrahydropyridine (MPTP) to mice 255 News Items
Number 3 257 Editorial Anna Starzec, Mohieddine Moumni, Gisdle D'Angelo-Bernard, Yannick Lerrant, Marian Jutisz and Raymond Counis
259 Cyclic AMP enhances gene expression, synthesis and release of newly synthesized alpha and luteinizing hormone beta subunits in cultured rat anterior pituitary cells
Chen Chen, Jin Zhang, Govindan Dayanithi, Jean-Didier Vincent and Jean-Marc Israel
265 Cationic currents on identified rat gonadotroph cells maintained in primary culture
B. Sion, E. Saint Dizier, J. Duval and M. L. Thieulant
277
Steroid receptors and regulation of LH and secretogranin II (GP87) secretion in pituitary cell aggregates
Bernardo Pensa, Marco Achilli, Mario Fontana, Anna Maria Caccuri and Doriano Cavallini
285
S-Aminoethyl-L-cysteine transaminase from bovine brain: purification to homogeneity and assay of activity in different regions of the brain
Marshall K. Cheung
293 The specificity of glutamate inhibition of protein synthesis in synaptosomal fractions from rat cerebral cortex
Marika Eller and Jaak J/irv
301
A. Kenessey, M. Banay-Schwartz, T. DeGuzman and A. Lajtha
307 Regional distribution of brain calpastatin and of calpain II. Activity with casein and with endogenous brain protein substrates
Makoto Naoi, Tsutomu Takahashi, Hasan Parvez, Ryosuke Kabeya, Eiich Taguchi, Keiko Yamaguchi, Yoko Hirata, Masayasu Minami and Toshiharu Nagatsu
315
N-Methylisoquinolinium ion as an inhibitor of tyrosine hydroxylas¢, aromatic L-amino acid decarboxylase and monoamine oxidase
Georges Vauquelin, Jacques De Keyser, Banyingela Kanyinda and Maurice Vanhaelen
321
(+)Tetrahydroanisocycline and (+)tetrahydropalmatine binding to D1 and D2 dopaminergic receptors in human putamen
N. A. Sharif, J. L. Nunes, A. D. Michel and R. L. Whiting
325 Comparative properties of the dopamine transport complex in dog and rodent brain: striatal [3H]GBR12935 binding and [3H]dopamine uptake
C. Moret, I. Pastrie and M. Briley
333
Phillip J. Robinson, Donald R. Gehlert, Enrico Sanna and Ingeborg Hanbauer
339 Two fractions enriched for striatal synaptosomes isolated by percoll gradient centrifugation: synaptosome morphology, dopamine and serotonin receptor distribution, and adenylate cyclase activity
Rainer Schwitzkowsky and Lfiszl6 Hetey
349 Characterization of synaptosomal dopamine release in rat and human brain after post-mortem storage and cryopreservation
M. K. Gaitonde and Elizabeth Murray
355 The effect of conditions of homogenization on the activity of pyruvate dehydrogenase and its stability in brain homogenates
Kinetics of N-methylscopolamine interaction with muscarinic receptor from rat cerebral cortex
Effects of scopolamine treatment and lesion of the nucleus basalis upon various cholinergic markers in the rat brain cortex
Index
vi Yoshiyuki Ohmori and Kinya Kuriyama
359
Negative coupling of ~,-aminobutyric acid (GABA)B receptor with phosphatidylinositol turnover in the brain
A. J. Cholewinski, J. C. Reid, A. M. McDermott and G. P. Wilkin
365
Purification of astroglial-cell cultures from rat spinal cord: the use of D-valine to inhibit fibroblast growth
371
Book Reviews
375
News Items
Claudia Martini, Rossella Pacini, Gino Giannaccini and Antonio Lucacchini
377
[3sS]TBPS binding to purified benzodiazepine~GABA ionophore receptor complex: the effect of GABA on the modulation exerted by benzodiazepine site ligands
Lois Winsky, Hiroyasu Nakata and David M. Jacobowitz
381
Identification of a calcium binding protein highly localized to the cochlear nucleus
S. C. R. Lummis and D. B. Sattelle
391
Insect nervous system [3H]saxitoxin binding sites: characterization and target size
Giuseppe Arienti, Giuseppe Fratto, Gian Luigi Piccinin, Maria Teresa Ramacci, Licia Pacifici, Mariangela Rossi and Lanfranco Corazzi
397
Valproic acid and bicuculline affect the formation of glycerolipid in rat brain
Andrzej Szutowicz, Hanna Bielarczyk, Danuta Sosnowska and Barbara Ciszek
403
Regulation of citrate metabolism and acetylcholine synthesis by Ca 2+ in rat brain synaptosomes
M. Thereza R. Perez and Berndt Ehinger
411
Multiple neurotransmitter systems influence the release of adenosine derivatives from the rabbit retina
Junya Tanaka, Kunitoshi Tada, Masatoshi Takeda, Shiro Hariguchi and Tsuyoshi Nishimura
421
Effect of metallic cations and pH on reassembly of glial fibrillary acidic protein
P. C. Hopkins, I. S. Kay and W. E. Davies
429
A rapid method for the determination of taurine in biological tissue
R. Grimaldi, C. G. Eriksson, P. Eneroth, L. F. Agnati and K. Fuxe
433
Evidence for nuclear ornithine decarboxylase activity in different brain regions of the male rat
H~16ne Fournier and Roger F. Butterworth
439
Effects of maternal thiamine deficiency on the development of thiamine-dependent enzymes in regions of the rat brain
H. Lara and J. Belmar
445
Biochemical evidence for the presence of small and large noradrenergic storage vesicles isolated from cat ovary in isoosmotic conditions. Distribution of dopamine-/~-hydroxylase activity
Riccardo Ghidoni, Amelia Fiorilli, Marco Trinchera, Bruno Venerando, Vanna Chigorno and Guido Tettamanti
455
Uptake, cell penetration and metabolic processing of exogenously administered GM 1 ganglioside in rat brain
ltaru Toyoshima, Akio Yamamoto, Osamu Masamune, Shoji Yamada and Mei Satake
467
Difference in phosphorylation of neurofilament proteins in motor neurons and spinal ganglion cells
Bernadette Earley, Anat Biegon and B. E. Leonard
475
Quantitative autoradiographic analysis of muscarinic receptors and quantitative histochemistry of acetylcholinesterase in the rat brain after trimethyltin intoxication
Gary A. Walter and John W. Phillis
485
5-Aminoimidazole-4-carboxamide riboside administration and purine release from the hypoxic/hypotensive rat cerebral cortex
Number 4
Index
vii
Rie Miyoshi, Shozo Kito, Hajime Ishida and Mika Nakashima
493
Modulation of dopamine DI receptor binding by neurotensin in the rat striatum
Masazumi Takeshita, Satoshi Yoshida and Toshitsugu Yubisui
497
Concomitant decrease in the elongation and condensation activities of very-long chain fatty acyl-CoA in jimpy mouse
Q. Pei, T. Zetterstr6m and M. Fillenz
503
Measurement of extracellular 5-HT and 5-HIAA in hippocampus of freely moving rats using microdialysis: long-term applications
A. Szab6, J. Nemcs6k, P. K~sa and K. Gulya
511
Muscarinic cholinergic components in the carp brain
Philippe Mailly, Amena Ben Youn6s-Chennoufi and Suzanne Bon
517
The monoclonal antibodies Elec-39, HNK-I and NC-I recognize common structures in the nervous system and muscles of vertebrates
D. Maysinger, B. Zorc, B. R. Leavitt, I. Butula, F. L. Chubb and A. C. Cuello
531
Structural analogs of hemicholinium: effects on cholinergic and GABAergic markers in the CNS
Jeffrey H. Boatright and P. Michael luvone
541
GABA and the regulation of serotonin N-acetyltransferasc activity in amphibian retina--I. Effects of GABA agonists and antagonists
Jeffrey H. Boatright and P. Michael Iuvone
549
GABA and the regulation of serotonin N-acetyltransferase activity in amphibian retina--II. The role of dopamine
Toshikuni Sasaoka, Norio Kaneda, Yoshikazu Kurosawa, Keisuke Fujita and Toshiharu Nagatsu
555
A Rapid Publication: Structure of human phenylethanolamine Nmethyltransferase gene: existence of two types of mRNA with different transcription initiation sites
Jerzy Z. Nowak and Ewa Zurawska
567
A Rapid Publication: Serotonin N-acetyltransferase (NAT) activity in hen retina and pineal gland: in vivo pharmacological induction at noon and antagonism of the light-evoked suppression at night
575
Book Review
577
News Items
N.C.I. 16/1--1
AUTHOR INDEX Achilli M. 285 Agnati L. F. 107, 433 Almqvist P. 73 Altsch/iller N. 97 Annaert W. 39 Arienti G. 397 Banay-Schwartz M. 307 Barat A. 115 Benfenati F. 107 Belmar J. 445 Biegon A. 475 Bielarczyk H. 403 Boatright J. H. 541, 549 Boiron F. 61 Bon S. 517 Bouchier C. 215 Briley M. 333 Brunelli M. 161 Budai D. 153 Butterworth R. F. 439 Butula I. 531 Caccuri A. M. 285 de Carvalho L. P. 9 Cassagne C. 61 Cattani M. 161 Cavallini D. 285 Charriere-Bertrand C. 215 Chen Chen 265 Cheung M. K. 293 Chigomo V. 455 Cholewinski A. J. 365 Chubb F. L. 531 Cipollini G. 161 Ciszek B. 403 Cohen G. 127 Corazzi L. 397 Counis R. 259 Crosswell S. 233 Cuello A. C. 531 D'Angelo-Bernard G. 259 Davies W. E. 429 Dawson R. M. 49 Dayanithi G. 265 De Deyn P. P. 39 De Keyser J. 321 De Potter W. P. 39 DeGuzman T. 307 Deschamps C.-M. 145 D'Hooge R. 39 Doble A. 1 Dopico A. M. 97 Dunglison G. F. 91 Duval J. 277 Earley B. 475
Ehinger B. 411 Eller M. 301 Eneroth P. 433 Eriksson C. G. 433 Evans J. M. 127 Fages C. 215 Fillenz M. 503 Fiorilli A. 455 Fontana M. 285 Fournier H. 439 Fowler C. J. 73 Fratto G. 397 Fujishiro K. 249 Fujita K. 555 Fuller G. 179 Fuxe K. 107, 433 Gaitonde M. K. 355 Gandolfi O. 223 Garcia-Gil M. 161 Garzon-Aburbeh A. 207 Gehlert D. R. 339 Ghidoni R. 455 Giannaccini A. 377 Gray P. J. 49 Greenfield S. A. 199 Gregg K. 179 Grimaldi R. 433 Guarnieri T. 223 Gulya K. 153, 511 Haggblad J. 199 Hagihara M. 249 Hall C. M. 185 Hanbauer I. 339 Hariguchi S. 421 Heape A. 61 Hetey L. 349 Hirata Y. 315 Hirouchi M. 33 Hopkins P. C. 429 Hunt A. 239 Huxtable R. J. 233 Ishida H. 493 Israel J.-M. 265 Israel M. 169 Iuvone P. M. 541, 549 Jacobowitz D. M. 381 Jaim-Etcheverry G. 97 J/irv J. 301 Jin Zhang 265 Jutisz M. 259 Kabeya R. 315 Kaneda N. 555 ix
Kanyinda B. 321 Karlsson J.-O. 185 K~isa P. 153, 157, 511 Katagiri T. 33 Kato T. 55 Kay I. S. 429 Kenessey A. 307 Kiss J. 239 Kito S. 493 Kouda T. 17 Kuriyama K. 33, 359 Kurosawa Y. 555 Kuwano R. 33 Lajtha A. 307 Lambolez B. 145 Lara H. 445 Larson D. L. 207 Leavitt B. R. 531 Lee H. S. 25 Le Gal la Salle G. 169 Leonard B. E. 475 Lerrant Y. 259 Lipkowski A. W. 207 L6pez J. J. $7 Lucacchini A. 377 Lucchi R. 223 Lummis S. C. R. 391 Madtes P. Jr 179 Mailly P. 517 Martini C. 377 Masamune O. 467 Mayo J. 97 Maysinger D. 531 McDermott A. M. 365 Meguri H. 17 Merlo Pich E. 107 Michaelson S. 49 Michel A. D. 325 Minami M. 315 Miyoshi R. 493 Montine T. J. 227 Morel N. 169 Moret C. 333 Moumni M. 259 Murray E. 355 Nagatsu T. 249, 315, 555 Nakashima M. 493 Nakata H. 381 Naoi M. 249, 315 Nemcs6k J. 511 Nicholls D. G. 191 Nilsson S. 73 Nishimura T. 421 Nowak J. Z. 567 Nunes J. L. 325
x Nunez J. 215 Ogita K. 17, 137 Ohgaki T. 17 Ohmori Y. 359 O'Neill C. 73 Pacifici L. 397 Pacini R. 377 Parker D. 233 Parvez H. 315 Pastrie I. 333 Patel A. J. 239 Pei Q. 503 Pensa B. 285 Perez M. T. R. 411 Perrier M. L. I Phillis J. W. 485 Piccinin G. L. 397 Pickut B. A. 39 Poli A. 223 Portoghese P. S. 207 le Prince G. 215
Index Sasaoka T. 555 Satake M. 467 Sattelle D. B. 391 Schoepp D. D. 131 Schwitzkowsky R. 349 Shanley B. C. 91 Sharif N. A. 325 Sion B. 277 Sosnowska D. 403 Sourkes T. L. 227 Starzec A. 259 Synguelakis M. 169 Szab6 A. 51 l Szutowicz A. 403
Rakonczay Z. 157 Ramacci M. T. 397 Ramirez G. 115 Reid J. C. 365 Robinson P. J. 339 Roncada P. 223 Rosario P. 115 Rossi M. 397 Rossier J. 145 Ruggeri M. 107
Tada K. 421 Taguchi E. 315 Takahashi A. 249 Takahashi T. 315 Takahashi Y. 33 Takeda K. 55 Takeda M. 421 Takeshita M. 497 Takita M. 55 Tan C. H. 25 Tanaka J. 421 Tardy M. 215 Taylor S. J. 199 Teo W. L. 25 Tettamanti G. 455 Thieulant M. L. 277 Tongiorgi E. 161 Toyoshima I. 467 Trinchera M. 455
Saint Dizier E. 277 Sanna E. 339
Uchida S. 17 Uchiumi F. 55
Ungerstedt U. 107 Upsher C. M. 49 Vanhaelen M. 321 Vauquelin G. 321 Venerando B. 455 Verzwijvelen A. 39 Villani L. 223 Vincent J.-D. 265 Volterra V. 107 Walter G. A. 485 Whiting R. L. 325 Wiehager B. 73 Wilce P. A. 91 Wilk E. K. 81 Wilk S. 81 Wilkin G. P. 365 Wilkinson R. J. 191 Winblad B. 73 Winsky L. 381 Wolff J. R. 157 Wong P. T.-H. 25 Yamada K. 17 Yamada S. 467 Yamaguchi K. 315 Y a m a m o t o A. 467 Yoneda Y. 17, 137 Yoshida S. 497 Younds-Chennoufi A. B. 517 Yubisui T. 497 Zetterstr6m T. 503 Zieher L. M. 97 Zini 1. 107 Zorc B. 531 Zurawska E. 567
SUBJECT INDEX Acetylcholinesterase - in c a r p b r a i n , 511 Acetylcholine - in c a r p brain, 511 Acetylcholine release, 9 Acetylcholine release - modulation by muscarinic receptors, 9 Acetylcholine s y n t h e s i s - e f f e c t of c a l c i u m , 403 Acetylcholine s y n t h e s i s - in s y n a p t o s o m e s , 403 Acetylcholinesterase - a l l o s t e r i c p r o p e r t i e s , 49 Acetylcholinesterase characterisation of Triton solubilised form, 49 Acetylcholinesterase - e f f e c t of NaBr, 157 Acetylcholinesterase - e f f e c t of t r i m e t h y l t i n i n t o x i c a t i o n , 475 Acetylcholinesterase - histochemistry, 475 Acetylcholinesterase - in s u p e r i o r c e r v i c a l g a n g l i o n , 157 Acetylcholinesterase - k i n e t i c p r o p e r t i e s , 49 Acetylcholinesterase - m o l e c u l a r forms, 157 Acetylcholinesterase - m o n o c l o n a l a n t i b o d i e s , 517 A d e n o s i n e d e r i v a t i v e s - r e l e a s e , 411 A d e n y l a t e c y c l a s e a c t i v i t y - in s y n a p t o s o m e s , 339 A l e u r i a l e c t i n - b i n d s to r e c e p t o r s , 185 5-aminoimidazole-4-carboxamide riboside - effect on purine r e l e a s e , 485 S-aminoethyl-L-cysteine transaminase purification and characterisation, 285 A n t i b o d i e s - to p r o t e o l i p i d s , 169 Aromatic-L-amino acid decarboxylase inhibited by Nmethyliosolinuim, 315 A s t r o c y t e c u l t u r e s - e x p r e s s i o n of m R N A s , 215 A s t r o c y t e s - e f f e c t of t h y r o i d d e f i c i e n c y on cell, 239 A s t r o g l i a l cell c u l t u r e s - f r o m s p i n a l cord, 365 Autoradiography - of m u s c a r i n i c r e c e p t o r s , 91, 475 A x o n a l t r a n s p o r t - in r e t i n a l g a n g l i o n cells, 185 A x o n a l t r a n s p o r t - Of A l e u r i a l e c t i n r e c e p t o r s , 185 A x o n a l t r a n s p o r t - of n o r a d r e n a l i n e , dopamine-hydroxylase and NPY, 39 A x o n a l t r a n s p o r t - of r e c e p t o r s , 185 Benzodiazepine c o m p l e x - b i n d i n g of ( 3 s S ) T B P S , Benzodiazepine r e c e p t o r , 145 Benzodiazepines - interaction with a histadine Bicuculline - e f f e c t on g l y c e r o l i p i d , 397 B i n d i n g - of 3 H - G A B A , 115 B i n d i n g - of a H - m u s c i m o l , 179 B i n d i n g - of 3 H - t r y p t o p h a n , 25
377 residue,
C - A M P - e n h a n c e s g e n e e x p r e s s i o n , 259 C-AMP dependent phosphorylation, 161 C - D N A c l o n i n g - of G A B A a r e c e p t o r , 33 C a l c i u m - e f f e c t on a c e t y l c h o l i n e m e t a b o l i s m , 403 C a l c i u m - e f f e c t on c i t r a t e m e t a b o l i s m , 403 C a l c i u m b i n d i n g p r o t e i n , 381 C a l m o d u l i n - e f f e c t of 3 H - g l u t a m a t e a c c u m u l a t i o n , 17 C a l m o d u l i n - e f f e c t on 3 H - g l u t a m a t e b i n d i n g , 17 C a l p a i n II - a c t i v i t y w i t h c a s e i n , 307 C a l p a i n II - r e g i o n a l d i s t r i b u t i o n , 307 C a l p a s t a t i n - a c t i v i t y in p r e s e n c e of casein, 307 Calpastatin - regional distribution, 307 ~-carbolines - interaction with benzodiazepine receptor, C a r p b r a i n - m u s c a r i n i c system, 511 C a s e i n - e f f e c t on c a l p a i n II a c t i v i t y , 307 C a s e i n - e f f e c t on c a l p a s t a t i n a c t i v i t y , 307 Catecholamine l e v e l s - e f f e c t of x - i r r a d i a t i o n , 97 C a t i o n i c c u r r e n t s - of g o n a d o t r o p h cells, 265 C a t i o n s - e f f e c t on GFAP, 421 3 H - C D - b i n d i n g to m u s c a r i n i c r e c e p t o r s , 333 Cholecystokinin o c t o p e p t i d e s u l f a t e - i m m u n o a s s a y , 55 Choline acetyltransferase - in c a r p brain, 511 xi
145
145
xii
Index
C h o l i n e r g i c m a r k e r s - e f f e c t of h e m i c h o l i n i u m analogs, 531 C h o l i n e s t e r a s e - release, 199 Cholinesterase activity - measurement, 199 3H-(+)-cis-methyldioxolane - see sH-CD, 333 C i t r a t e m e t a b o l i s m - e f f e c t of calcium, 403 C i t r a t e m e t a b o l i s m - in s y n a p t o s o m e s , 403 C l o n i n g - of h u m a n G A B A a r e c e p t o r , 33 C o c h l e a r n u c l e u s - l o c a l i s a t i o n of c a l c i u m b i n d i n g , 381 Cryopreservation - d o p a m i n e r e l e a s e , 349 2',3'-cyclic nucleotide 3'phosphohydrolase - in g l i a l cells, C y c l o s p o r i n A - e n h a n c e s n e u r o t o x i c i t y of MPTP, 249
239
D - v a l i n e - i n h i b i t s f i b r o b l a s t g r o w t h , 365 D1 r e c e p t o r s - b i n d i n g studies, 321 D2 r e c e p t o r s - b i n d i n g studies, 321 D o p a m i n e - a c t i o n on s e r o t o n i n - N - a c e t y l t r a n s f e r a s e , 549 D o p a m i n e b e h a v i o u r s , 107 D o p a m i n e c o n t e n t - e f f e c t of x - i r r a d i a t i o n , 97 D o p a m i n e n e u r o n e s - e f f e c t of n e u r o t o x i n s , 127 D o p a m i n e r e c e p t o r s - on s y n a p t o s o m e s , 339 D o p a m i n e r e l e a s e - e f f e c t of u r i d i n e , 107 D o p a m i n e r e l e a s e - f r o m s t r i a t a l slices, 107 Dopamine release - from synaptosomes, 349 D o p a m i n e u p t a k e sites - b i n d i n g of 3 H - G B R 12935, 325 Dopamine-~-hydoxylase - a x o n a l t r a n s p o r t , 39 Dopamine-~-hydoxylase - subcellular distribution, 39 Dopamine-~-hydroxylase a c t i v i t y - in v e s i c l e s , 445 D o p a m i n e r g i c n e u r o n e s - e f f e c t of MPP+, 223 E l e c - 3 9 - m o n o c l o n a l a n t i b o d y , 517 E t h a n o l - e f f e c t on m u s c a r i n i c r e c e p t o r s , 91 E x c i t a t o r y a m i n o a c i d r e c e p t o r s - a n d p r o t e i n k i n a s e C, 131 E x c i t a t o r y a m i n o acids, 1 Excitatory amino acids - phosphoinositide h y d o l y s i s , 131 E x c i t a t o r y a m i n o a c i d s - r e c e p t o r s l i n k e d to i n o s i t o l p h o s p h a t e s , Excitatory amino acids - receptors, 1 E x p r e s s i o n of G F A P mRNAs, 215 E x p r e s s i o n of t u b u l i n mRNAs, 215 F a t t y acyl g r o u p s - f r o m p h o s p h a t i d e s to o p i a t e ligands, F a t t y a c y l - C o A - e l o n g a t i o n a n d c o n d e n s a t i o n , 497 F a t t y a c y l - C o A - in j i m p y m o u s e , 497 F i b r o b l a s t g r o w t h - i n h i b i t e d b y D - v a l i n e , 365
207
3 H - G A B A b i n d i n g - in D r o s o p h i l a CNS m e m b r a n e s , 115 GABA regulates serotonin-N-acetyltransferase, 549 GABA r e g u l a t i o n of s e r o t o n i n - N - a c e t y l t r a n s f e r a s e , 541 G A B A d i s p l a c e a b l e S H - m u s c i m o l b i n d i n g , 179 G A B A a r e c e p t o r - c l o n i n g of c-DNA, 33 GABAb receptors - negative coupling with phosphatidylinositol t u r n o v e r , 359 G a n g l i o s i d e - uptake, 455 3 H - G B R 12935 b i n d i n g - to d o p a m i n e u p t a k e sites, 325 Sene e x p r e s s i o n - e f f e c t of c-AMP, 259 G e n e s t r u c t u r e - of p h e n y l e t h a n o l a m i n e - N - m e t h y l t r a s f e r a s e , 555 G F A P - e f f e c t of m e t a b o l i c c a t i o n s , 421 GFAP e f f e c t of pH, 421 G F A P mRNAs, 215 G l i a l f i b r i l l a r y a c i d p r o t e i n - see GFAP, 421 3 H - g l u t a m a t e - a c c u m u l a t i o n a n d b i n d i n g , 17 3 H - g l u t a m a t e a c c u m u l a t i o n - e f f e c t of c a l m o d u l i n , 17 3 H - g l u t a m a t e b i n d i n g - f r o m rat a d r e n a l , 137 3 H - g l u t a m a t e b i n d i n g - q u i s q u a l a t e s e n s i t i v e , 137 3 H - g l u t a m a t e u p t a k e - e f f e c t of c a l m o d u l i n , 17 G l u t a m a t e - i n h i b i t s p r o t e i n s y n t h e s i s , 293 G l u t a m i n e s y n t h e t a s e - in g l i a l cells, 239 -
-
-
1
Index
xiii
G l y c e r o l i p i d - e f f e c t of b i c u c u l l i n e , 3~-7 G l y c e r o l i p i d - e f f e c t of v a l p r o i c acid, 397 G l y c e r o l i p i d - f o r m a t i o n , 397 GMI g a n g l i o s i d e - u p t a k e , 455 G o n a d o t r o p h c e l l s - c a t i o n i c c u r r e n t s , 265 G o n a d o t r o p h c e l l s - in c u l t u r e , 265 H a l o p e r i d o l t r e a t m e n t - u r i d i n e e f f e c t s on b e h a v i o u r , 107 Hemicholinium a n a l o g s - e f f e c t on c h o l i n e r g i c a n d a n d GABAergic systems, 531 H i s t i d i n e r e s i d u e - of B e n z o d i a z e p i n e r e c e p t o r , 145 H N K - I - m o n o c l o n a l a n t i b o d y , 517 H P L C - f o r d e t e r m i n i n g t a u r i n e , 429 5-HT - a n a l y s i s b y m i c r o d i a l y s i s , 503 5-HT - in f r e e l y m o v i n g rats, 503 5-hydroxyindoleacetic acid - analysis by microdialysis, 503 5-hydroxyindoleacetic a c i d - in f r e e l y m o v i n g rats, 503 6-hydroxydopamine - e f f e c t on d o p a m i n e n e u r o n e s , 127 6-hydroxydopamine - n e u r o t o x i n , 127 Hypoxic/hyptensive rats - r e l e a s e of p u r i n e s , 485 I m m u n o a s s a y - Of c h o l e c y s t o k i n i n , 55 I n o s i t o l p h o s p h a t e - in n e o n a t a l rat s t r i a t u m , 1 I n o s i t o l p h o s p h a t e - r e c e p t o r s of e x c i t a t o r y a m i n o acids, 1 Inositol phosphates - receptors, 1 I n o s i t o l p h o s p h o l i p i d b r e a k d o w n - in S H - S Y S Y cells, 73 I n s e c t n e r v o u s s y s t e m - b i n d i n g of 3 H - s a x i t o x i n , 391 Jimpy
mouse
- fatty
acyl-CoA,
497
Luteinizing Luteinizing
hormone hormone
- r e g u l a t i o n of s t e r o i d r e c e p t o r s , - s y n t h e s i s of s u b u n i t s , 259
277
MAO -inhibited by N-methylisoquinolinium ion, 315 Methylserotonin - in s y n a p t o s o m e s , 227 l-methyl-4-phenylpyridiniu~ ion [MPP+] - e f f e c t on dopaminergic n e u r o n e s in g o l d f i s h retina, 223 N-methyl-4,phenyl-l,2,3,6-tetrahydropyridine (MPTP) - see, 249 N-methylisoquinolinium ion - i n h i b i t o r of a r o m a t i c - L - a m i n o acid decarboxylase, 315 N-methylisoquinolinium ion - i n h i b i t o r of MA0, 315 N-methylisoquinolinium ion - i n h i b i t o r of t y r o s i n e - h y d r o x y l a s e , 315 N-methylscopolamine - b i n d i n g , 301 N-methylscopolamine k i n e t i c s of i n t e r a c t i o n with muscarinic r e c e p t o r s , 301 M o d u l a t i o n - of a c e t y l c h o l i n e release, 9 Monoaminergic l e v e l s - e f f e c t of M P P + in retina, 223 M o n o c l o n a l a n t i b o d i e s - to a c e t y l c h o l i n e s t e r a s e , 517 MPP+ e f f e c t on m o n o a m i n e l e v e l s in g o l d f i s h retina, 223 MPTP neurotoxicity - e n h a n c e d b y c y c l o s p o r i n A, 249 MRNA of p h e n y l e t h a n o l a m i n e - N - m e t h y l t r a n s f e r a s e , 555 MRNAs f r o m t u b u l i n a n d G F A P in a s t r o c y t e s , 215 M u s c a r i n i c r e c e p t o r s - e f f e c t of e t h a n o l , 91 M u s c a r i n i c a n t a g o n i s t s - e f f e c t on a u t o r e c e p t o r s , 153 Muscarinic autoreceptors, 153 Muscarinic autoreceptors - e f f e c t of a n t a g o n i s t s , 153 M u s c a r i n i c c o m p o n e n t s - in c a r p brain, 511 Muscarinic receptors, 9 Muscarinic receptors - autoradiography, 91 M u s c a r i n i c r e c e p t o r s - b i n d i n g of 3 H - Q N B a n d 3H-CD, 333 M u s c a r i n i c r e c e p t o r s - c o u p l e d to i n o s i t o l p h o s p h a t e s , 73 M u s c a r i n i c r e c e p t o r s - do not s e n s i t i z e , 9 M u s c a r i n i c r e c e p t o r s - e f f e c t of s c o p o l a m i n e t r e a t m e n t , 333 M u s c a r i n i c r e c e p t o r s - e f f e c t of t r i m e t h y l tin i n t o x i c a t i o n , 475 Muscarinic receptors - interaction with N-methylscopolamine, 301 Muscarinic receptors - modulates acetylcholine release, 9 Muscarinic receptors - quantitative autoradiography, 475 S H - m u s c i m o l b i n d i n g - s e n s i t i v i t y to GABA, 179 -
-
-
xiv
Index N a B r t r e a t m e n t - e f f e c t of a c e t y l c h o l i n e s t e r a s e , 157 NC-I - monoclonal-antibody, 517 Neurofilament proteins - phosphorylation, 467 N e u r o f i l a m e n t p r o t e i n s - i n n e u r o n e s , 467 N e u r o p e p t i d e Y - s u b c e l l u l a r d i s t r i b u t i o n , 39 N e u r o t o x i n s - e f f e c t o n d o p a m i n e n e u r o n e s , 127 N o r a d r e n a l i n e - a x o n a l t r a n s p o r t , 39 N o r a d r e n a l i n e - s u b c e l l u l a r d i s t r i b u t i o n , 39 N o r a d r e n a l i n e c o n t e n t - e f f e c t of x - i r r a d i a t i o n , 97 N o r a d r e n e r g i c s t o r a g e v e s i c l e s , 445 N u c l e o t i d e s e q u e n c e s - of G A B A a r e c e p t o r a - s u b u n i t , 33 O l i g o d e n d r o c y t e s - e f f e c t of t h y r o i d d e f i c i e n c y o n c e l l m a r k e r s , 239 " O n - l i n e " - m e a s u r e of c h o l i n e s t e r a s e a c t i v i t y r e l e a s e , 199 O p i a t e l i g a n d s - t r a n s f e r of f a t t y a c y l g r o u p s f r o m p h o s p h a t e s , 207 O r n i t h i n e d e c a r b o x y l a s e a c t i v i t y , 433 O r n i t h i n e d e c a r b o x y l a s e a c t i v i t y - s u b c e l l u l a r d i s t r i b u t i o n , 433 P a l m i t a t e - in n o r m a l a n d t r e m b l e r m i c e , 61 P a l m i t a t e - u p t a k e a n d m e t a b o l i s m , 61 P a t c h - c l a m p - of g o n a d o t r o p h s , 265 Phenylethanolamine-N-methyltransferase g e n e - m R N A , 555 Phenylethanolamine-N-methyltransferase g e n e - s t r u c t u r e , 555 P h o s p h a t i d e s - t r a n s f e r of f a t t y a c y l g r o u p s to o p i a t e l i g a n d s , 207 Phosphatidylinositol turnover - negatively coupled with GABAb r e c e p t o r s , 359 P h o s p h o i n o s i t i d e h y d r o l y s i s - e f f e c t of e x c i t a t o r y a m i n o acids, 131 P h o s p h o r y l a t i o n - of n e u r o f i l a m e n t p r o t e i n s , 467 P h o s p h o r y l a t i o n - c - A M P d e p e n d e n t p r o c e s s , 161 P h o s p h o r y l a t i o n - in l e e c h CNS, 161 P h o s p h o r y l a t i o n - of 79 k D a p r o t e i n , 161 P i t u i t a r y c e l l a g g r e g a t e s , 277 P i t u i t a r y c e l l s - in t i s s u e c u l t u r e , 259 P r o t e i n k i n a s e C - a n d n e o n a t a l e x c i t a t o r y a m i n o a c i d s , 131 P r o t e i n s y n t h e s i s - i n h i b i t e d b y g l u t a m a t e , 293 P r o t e o l i p i d a n t i g e n s - at T o r p e d o n e u r o m u s c u l a r s y n a p s e s , 169 Proteolipids - immunohistochemical l o c a l i s a t i o n , 169 Purine release effect of 5-aminoimidazole-4-carboxamide r i b o s i d e , 485 Purine release - from hypoxic/hypotensive r a t c o r t e x , 485 Pyroglutamyl peptidase II a thyrotropin release hormone d e g r a d i n g e n z y m e , 81 P y r o g l u t a m y l p e p t i d a s e II - p r o p e r t i e s , 81 P y r u v a t e d e h y d r o g e n a s e - a c t i v i t y , 355 3H-(-)-quinuclidinyl Quisqualate - effect
b e n z i l a t e - s e e 3 H - Q N B , 333 on 3 H - g l u t a m a t e b i n d i n g , 137
R e c e p t o r s - a n d a x o n a l t r a n s p o r t , 185 R e c e p t o r s - f o r s t e r o i d s , 277 Receptors - to excitatory amino acids, 1 R e l e a s e - of a c e t y l c h o l i n e , 9 R e l e a s e - of a d e n o s i n e d e r i v a t i v e s , 4 1 1 R e t i n a - d o p a m i n e r g i c n e u r o n e s , 223 R e t i n a - r e l e a s e of a d e n o s i n e d e r i v a t i v e s , 4 1 1 Retina - serotonin-N-acetyltransferase, 541 3 H - s a x i t o x i n - b i n d i n g sites, 391 3 H - s a x i t o x i n - b i n d i n g to s o d i u m c h a n n e l , 391 S c o p o l a m i n e - c h r o n i c e f f e c t o n m u s c a r i n i c r e c e p t o r s , 333 S e c r e t o g r a n i n II - a g o n a d o t r o p h p o l y p e p t i d e , 277 S e c r e t o g r a n i n II - r e g u l a t e d b y s t e r o i d r e c e p t o r s , 277 S e r o t o n i n r e c e p t o r s - o n s y n a p t o s o m e s , 339 Serotonin-N-acetyltransferase - in r e t i n a , 541, 549 Serotonin-N-acetyltransferase - r e g u l a t e d b y GABA, 541, 549 S H - S Y S Y n e u r o b l a s t o m a c e l l s - m u s c a r i n i c r e c e p t o r s , 73 S o d i u m c h a n n e l s - b i n d i n g of 3 H - s a x i t o x i n , 391
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S t e r o i d r e c e p t o r s , 277 S t e r o i d r e c e p t o r s - r e g u l a t e l u t e i n i z i n g h o r m o n e , 277 Steroid receptors - regulate secretogranin II, 277 S y n a p t o s o m a l d o p a m i n e r e l e a s e - f r o m c r y o p r e s e r v e d tissue, 349 S y n a p t o s o m a l d o p a m i n e r e l e a s e - f r o m p o s t m o r t e m brain, 349 Synaptosomes - acetylcholine s y n t h e s i s , 403 S y n a p t o s o m e s - b e h a v i o u r of a - m e t h y l s e r o t o n i n , 227 S y n a p t o s o m e s - d o p a m i n e a n d s e r o t o n i n r e c e p t o r d i s t r i b u t i o n , 339 S y n a p t o s o m e s - d o p a m i n e r e l e a s e , 349 S y n a p t o s o m e s - f r o m rat c e r e b r a l cortex, 293 S y n a p t o s o m e s - m o r p h o l o g y in d i f f e r e n t f r a c t i o n s , 339 S y n a p t o s o m e s - p r o t e i n s y n t h e s i s , 293 S y n a p t o s o m e s - a d e n y l a t e c y c l a s e a c t i v i t y , 339 S y n a p t o s o m e s - in d i f f e r e n t f r a c t i o n s , 339 Taurine - determination, 429 (35S)t-butyl bicylophosphosphorothionate - see ( 3 5 S ) T B P S ( 3 s S ) T B P S - b i n d i n g to b e n z o d i a z e p i n e c o m p l e x , 377 (±)Tetrahydroanisocycline - b i n d i n g to D1 a n d D2 r e c e p t o r s , 321 (±)Tetrahydropalmatine - b i n d i n g to D1 a n d D2 r e c e p t o r s , 321 T h i a m i n e d e f i c i e n c y - e f f e c t on s p e c i f i c e n z y m e s , 439 T h i a m i n e d e p e n d e n t e n z y m e s , 439 T h y r o i d d e f i c i e n c y - a n d m a t u r a t i o n of g l i a l cells, 239 T h y r o i d d e f i c i e n c y - r e l a t e d to m a r k e r s for a s t r o c y t e s , 239 Thyrotropin release hormone degrading enzyme - pyroglutamyl p e p t i d a s e II, 81 Torpedo neuromuscular s y n a p s e s - p r o t e o l i p i d a n t i g e n , 169 T r e m b l e r m i c e - u p t a k e a n d m e t a b o l i s m of p a l m i t a t e , 61 T r i m e t h y l t i n i n t o x i c a t i o n - e f f e c t on m u s c a r i n i c r e c e p t o r s , 475 3 H - t r y p t o p h a n - b i n d i n g , 25 T u b u l i n m R N A s , 215 Tyrosine hydroxylase - inhibited by N-methylisoquinolinium ion, 315 U p t a k e - of p a l m i t a t e , 61 U r i d i n e - e f f e c t on d o p a m i n e r e l e a s e a n d b e h a v i o u r , 107 U r i d i n e e f f e c t s - f o l l o w i n g h a l o p e r i d o l t r e a t m e n t , 107 U r i d i n e t r e a t m e n t - h a l o p e r i d o l e f f e c t s on b e h a v i o u r , 107 Valproic Vesicles Vesicles Vesicles
a c i d - e f f e c t on g l y c e r o l i p i d , 397 - containing noradrenaline, 445 - dopamine-~-hydroxylase, 445 - f r o m cat ovary, 445
X-irradiation
- effect
on d o p a m i n e
and noradrenaline,
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