Cumulative Nce Introduction Index, 1983-1992

Cumulative NCE Introduction Index, 1983-1992

GENERIC NAME

INDICATION

antidiabetic antiinflammatory hypoammonuric hypolipidemic antipsoriatic antihistamine antiseptic psychostimulant antiinflammatory AF-2259 afloqualone muscle relaxant antihypertensive alacepril alclometasone dipropionate topical antiinflammatory alfentanil HCI analgesic antihypertensive alfuzosin HCI enzyme alglucerase analgesic alminoprofen alpha-I antitrypsin protease inhibitor anxiolytic alpidem antimigraine alpiropride thrombolytic alteplase antiinflammatory amfenac sodium topical antiinflammatory aminoprofen amisulpride antipsychotic antiasthmatic amlexanox antihypertensive amlodipine besylate topical antifungal amorolfine hydrochloride antihypertensive amosulalol cardiotonic amrinone antineoplastic amsacrine calcium regulator APD antiglaucoma apraclonidine HCI thrombolytic APSAC antibiotic arbekacin antithromobotic argatroban antihypertensive arotinolol HCI antimalarial artemisinin antibiotic aspoxicillin antihistamine astemizole antibiotic astromycin sulfate antiparasitic atovaquone chrysotherapeutic auranofin antiacne azelaic acid antihistamine azelastine HCI antibiotic azithromycin diuretic azosemide antibiotic aztreonam bronchodilator bambuterol antihypertensive barnidipine hydrochloride hypolipidemic beclobrate antiglaucoma befunolol HCI antihypertensive benazepril hydrochloride antiulcer benexate HCI antihypertensive benidipine hydrochloride platelet aggreg. inhibitor beraprost sodium antihypertensive betaxolol HCI antihypertensive bevantolol HCI acarbose aceclofenac acetohydroxamic acid acipimox acitretin acrivastine adamantanium bromide adrafinil

YEAR INTRODUCED ARMC VOL.. PAGE

1990 1992 1983 1985 1989 1988 1984 1986 1987 1983 1988 1985 1983 1988 I991 1983 1988 1991 1988 1987 1986 1990 1986 1987 1990 1991 1988 1983 1987 1987 1988 1987 1990 1990 1986 1987 1987 1983 1985 1992 1983 1989 1986 I988 1986 1984 1990 1992 1986 1983 1990 1987 1991 1992 1983 1987

26, 28, 19, 21, 25, 24, 20, 22, 23, 19, 24, 21, 19, 24, 27, 19, 24, 27, 24, 23, 22, 26, 22, 23, 26. 27, 24, 19, 23, 23, 24, 23, 26, 26, 22, 23, 23, 19, 21, 28, 19, 25, 22, 24, 22, 20, 26, 28, 22, 19, 26, 23, 27, 28, 19, 23,

297 325 313 323 309 295 315 315 325 313 296 323 314 296 321 314 297 322 296 326 315 298 316 327 298 322 297 314 327 326 297 326 298 299 316 327 328 314 324 326 314 310 316 298 316 315 299 326 317 315 299 328 322 326 315 328

Cumulative NCE Introduction Index. 1983-1992

GENERIC NAME

INDiCATlON

bifemelane HCI binfonazole binlfibrate bisantrene hydrochlorlde blsoproiol fumarate bopindoiol brotizolam brovincamine fumarate buciilamlne bucladeslne sodium budralazlne bunazosin HCI buproplon HCI buserelln acetate buspirone HCi butenafine hydrochloride butlbufen butoconazole butoctamide butyi flufenamate cadexomer iodine cadralazine calcipotriol camostat mesylate carboplatin carumonam carvedllol cefbuperazone sodium cefdinir cefetamet plvoxil hydrochloride cefixime cefmenoxlme HCI cefminox sodium cefodlzime sodium cefonicld sodium ceforanide cefotetan disodium cefotiam hexetll hydrochloride cefpimizoie cefpirarnide sodium cefpirome sulfate cefpodoxime proxetll cefprozil ceftazidlme cefteram pivoxll ceftibuten cefuroxime axetil cefuzonam sodium ceiiprolol HCI centchroman centoxin cetirizlne HCI chenodioi choiine alfoscerate

nootroplc hypnotlc hypoiipidemic antineoplastic antlhypertensive antihypertensive hypnotic cerebral vasodilator lmmunomodulator cardiostimuiant antihypertensive antihypertensive antidepressant hormone anxioiytic topical antifungal antiinflammatory topical antifungal hypnotic topical antiinflammatory wound healing agent hypertensive antipsorlatic antineoplastic antibiotic antlbiotic antihypertensive antiblotic antlbiotic antibiotic

1987 1983 1986 1990 1986 1985 1983 1986 1987 1984 1983 1985 1989 1984 1985 1992 1992 1986 1984 1983 1983 1988 1991 1985 1986 1988 1991 1985 1991 1992

26, 22, 21, 19, 22, 23, 20, 19, 21, 25, 20, 21, 28, 28, 22, 20, 19, 19, 24, 27, 21. 22, 24, 27, 21, 27, 28,

329 315 317 300 317 324 315 317 329 316 315 324 310 316 324 327 327 318 316 316 316 298 323 325 318 298 323 325 323 327

antlbiotic antibiotic antibiotic antibiotic antibiotic antibiotic antibiotic antibiotic

1987 1983 1987 1990 1984 1984 1984 1991

23, 19, 23, 26, 20, 20, 20, 27,

329 316 330 300 316 317 317 324

antibiotic antibiotic antibiotic antibiotic antibiotic antibiotic antibiotic antibiotic antibiotic antibiotic ant1hypertensive antiestrogen

1987 1985 1992 1989 1992 1983 1987 1992 1987 1987 1983 1991 1991 1987 1983 1990

23, 21, 28, 25, 28, 19, 23, 28, 23, 23, 19, 27, 27, 23, 19, 26,

330 325 328 310 328 316 330 329 331 331 317 324 325 331 317 300

antihistamine anticholeiithogenic nootropic

YEAR iNTRODUCED ARMC VOL., PAGE 23, 19, 22,

Cumulative NCE Introduction Index, 198Z-1992

GENERIC NAME

INDICATION

cibenzoline cicletanine cilostazol cimetropium bromide cilazapril cinitapride ciprofibrate ciprofloxacln cisapride citalopram clarithromycin clobenoside cloconazole HCI clodronate disodium cloricromen clospipramine hydrochloride cyclosporine dapiprazole HCI defibrotide deflazacort delapril denopamine deprodone propionate desflurane dexrazoxane dezocine diacerein didanosine dilevalol disodium pamidronate divistyramlne dopexamine doxacurium chloride doxazosln mesylate doxefazepam doxifluridine doxofylllne dronabinol droxicam droxidopa ebastine emorfazone enalapril maleate enalaprilat encainide HCI enocitabine enoxacin enoxaparin enoximone enprostil epalrestat eperisone HCi epidermal growth factor epirubicin HCI epoprostenol sodium eptazocine HBr

antiarrhythmic antihypertensive antithrombotic antispasmodic antihypertensive gastroprokinetic hypollpidemic antibacterial gastroprokinetic antidepressant antibiotic vasoprotective topical antifungal calcium regulator antithrombotic neuroleptic immunosuppressant antiglaucoma antithrombotic antiinflammatory antihypertensive cardiostimulant topical antiinflammatory anesthetic cardioprotective analgesic antirheumatic antiviral antihypertensive calcium regulator hypocholesterolemic cardiostimulant muscle relaxant antihypertensive hypnotic antineoplastic bronchodilator antinauseant antiinflammatory antiparkinsonian antihistamine analgesic antihypertensive antihypertensive antlarrhythmic antineoplastic antibacterial antithrombotic cardiostimulant antiulcer antidiabetic muscle relaxant wound healing agent antineoplastic platelet aggreg. inhib. analgesic

YEAR INTRODUCED ARMC VOL.. PAGE

1985 1988 1988 1985 1990 1990 I985 1986 1988 1989 I990 1988 1986 1986 1991 1991 1983 1987 1986 1986 1989 1988 1992 1992 1992 1991 1985 1991 1989 1989 1984 1989 1991 1988 1985 1987 1985 1986 1990 1989 1990 1984 1984 1987 1987 1983 1986 1987 1988 1985 1992 1983 1987 1984 1983 1987

325 299 299 326 301 301 326 318 299 31 1 302 300 31 8 319 325 325 317 332 319 319 31 1 300 329 329 330 326 326 326 31 1 312 317 312 326 300 326 332 327 319 302 312 302 31 7 31 7 332 333 318 320 333 301 327 330 318 333 318 318 334

Cumulative NCE Introducl;ion Index, lQ8Z-lQS2

GENERIC NAME erythromycin aclstrate erythropoietin esmolol HCI ethyl icosapentate etlzolam etodolac exifone factor Vlll famotidine felbinac felodipine fenbuprol fenticonazole nitrate filgrastim finasterlde fisalamine fleroxacln flomaxef sodium flosequlnan fluconazole fludarablne phosphate flumazenil flunoxaprofen fluoxetine HCI flupirtine maleate flutamlde fiutazolam fluticasone propionate flutoprazepam flutropium bromide fluvoxamine maleate formoterol fumarate foscarnet sodium fosfosal fosinoprll sodium fotemustine gallium nitrate gallopamil HCi ganciciovir gemeprost gestcdene gestrinone goserelin granisetron hydrochloride guanadrel sulfate halobetasol propionate halofantrine halometasone hydrocortisone aceponate hydrocortisone butyrate ibopamine HCI lbudilast idarubicin hydrochloride idebenone iioprost imipenem/cilastatin

INDICATION antibiotic hematopoetic antiarrhythmic antiihrombotic anxiolytic antiinflammatory nootropic hemostatic antiulcer topical antiinflammatory antihypertensive choieretic antifungal immunostimulant Sa-reductase inhibitor intestinal antiinflammatory antibacterial antibiotic cardiostimulant antifungal antineoplastic benzodiazepine antag. antiinflammatory antidepressant analgesic antineoplastic anxlolytic antiinflammatory anxiolytic antitussive antidepressant bronchodilator antiviral analgesic antihypertensive antineoplastic calcium regulator antianginal antiviral abortifacient progestogen antiprogestogen hormone antiemetic antihypertensive topical antiinflammatory antimalarial topical antiinflammatory topical antiinflammatory topical antiinflammatory cardiostimulant antiasthmatic antineoplastic nootropic platelet aggreg. Inhibitor antibiotic

YEAR INTRODUCED ARMC VOL.. PAGE 1988 1988 1987 1990 1984 1985 1988 1992 1985 1986 1988 1983 1987 1991 1992 1984 1992 1988 1992 1988 1991 1987 1987 1986 1985 1983 1984 1990 1986 1988 1983 1986 1989 1984 1991 1989 1991 1983 1988 1983 1987 1986 1987 1991 1983 1991 1988 1983 1988 1983 1984 1989 1990 1986 1992 1985

24, 24, 23, 26, 20, 21, 24, 28, 21, 22, 24, 19. 23. 27, 28, 20, 28, 24, 28, 24, 27, 23, 23, 22, 21, 19. 20, 26, 22, 24, 19, 22, 25, 20, 27, 25, 27, 19, 24, 19, 23. 22, 23, 27, 19, 27, 24. 19, 24, 19, 20, 25, 26, 22, 28, 21,

301 301 334 303 318 327 302 330 327 320 302 318 334 327 331 318 331 302 331 303 327 335 335 320 328 318 318 303 320 303 319 321 313 319 328 313 328 319 303 319 335 321 336 329 319 329 304 320 304 320 319 313 303 321 332 328

Cumulative NCE Introduction Index, 198S1992

GENERIC NAME indalpine indeloxazine HCI indobufen interferon, gamma interferon, gamma-la interferon gamma-1b interieukin-2 iprifiavone irsogladine isepamicin isofezoiac isoxicam isradipine itraconazole ivermectin ketanserin ketoroiac tromethamine iacidipine lamotrigine lansoprazole ienampicillin HCI ientinan leuprolide acetate levacecarnine HCi levobunoioi HCI levocabastine hydrochloride ievodropropizine lidamldine HCI iimaprost iisinopril lobenzarit sodium lodoxamide tromethamine iomefloxacin lonidamine loprazoiam mesylate ioracarbef ioratadine lovastatin loxoprofen sodium mabuterol HCi malotilate manidipine hydrochloride masoprocol medifoxamine fumarate mefloquine HCI meglutol meiinamide mepixanox meptazinol HCI metaclazepam metapramine mexazolam mifepristone milrinone miokamycin misoprostol

INDICATION antidepressant nootropic antithrombotic antiinflammatory antineoplastic irnmunostimulant antlneoplastic calcium regulator antiulcer antibiotic antiinflammatory antiinflammatory antihypertensive antifungal antiparasitic antihypertensive analgesic antihypertensive anticonvulsant antiulcer antibiotic immunostimulant hormone nootropic antiglaucoma antihistamine antitussive antiperistaltic antithrombotic antihypertensive antiinflammatory antiallergic ophthalmic antibiotic antineoplastic hypnotic antibiotic antihistamine hypocholesterolemic antiinflammatory bronchodilator hepatroprotective antihypertensive topical antineoplastic antidepressant antimalarial hypoiipidemic hypocholesteroiemic anaieptic analgesic anxiolytic antidepressant anxiolytic abortifacient cardiostimulant antibiotic antiulcer

YEAR iNTRODUCED ARMC VOL.,PAGE 1983 1988 1984 1989 1992 1991 1989 1989 1989 1988 1984 1983 1989 1988 1987 1985 1990 1991 1990 1992 1987 1986 1984 1986 1985 1991 1988 1984 1988 1987 1986 1992 1989 1987 1983 1992 1988 1987 1986 1986 1985 1990 1992 1986 1985 1983 1984 1984 1983 1987 1984 1984 1988 1989 1985 1985

19. 24, 20, 25, 28. 27, 25, 25. 25. 24, 20, 19, 25, 24, 23, 21 26, 27, 26, 28, 23, 22. 20. 22, 21 27, 24. 20, 24, 23, 22, 28, 25, 23, 19, 28, 24, 23, 22, 22, 21 26, 28, 22, 21, 19, 20. 20, 19, 23, 20, 20. 24. 25, 21 21, I

9

I

3

320 304 319 314 332 329 314 314 315 305 319 320 315 305 336 328 304 330 304 332 336 322 319 322 328 330 305 320 306 337 322 333 315 337 321 333 306 337 322 323 329 304 333 323 329 321 320 320 321 338 320 32 1 306 316 329 329

Cumulative NCE Introduction Index, 1983-1992

GENERIC NAME mivacurlum chlorlde mitoxantrone HCI mizorlblne moclobemlde momelasone furoate moricizlne hydrochloride moxonidine mupirocin muromonab-CD3 muzolimlne nabumetone nafamostat mesylate nafarelin acetate naftifine HCI naltrexone HCI nedocromil sodium nemonaprlde nicorandil nilutamide nilvadipine nimesulide nimodipine nipradilol nisoldipine nitrefazole nitrendlpine nlzatidlne nizofenzone fumarate nomegestroi acetate norfloxacln norgestimate octreotlde ofioxacin omeprazole ondansetron hydrochloride ornoprostil osalazine sodium oxaprozln oxcarbazepine oxiconazole nitrate oxiracetam oxitropium bromide ozagrel sodium paroxetine pefloxacin mesylate pegademase bovine pemiroiast potassium pentostatln pergolide mesylate perindoprll picotamide piketoprofen pllsicainide hydrochloride pimaprofen pinacidil pirarubicin

YEAR INTRODUCED Emuscle relaxant antlneopiastic Immunosuppressant antidepressant topical antilnflammatory antiarrhythmic , antihypertensive topical antibiotic immunosuppressant diuretic antiinflammatory protease inhibitor hormone antifungal narcotic antagonist antialiergic neuroieptic coronary vasodilator antineopiastic antihypertensive antiinflammatory cerebral vasodilator antihypertensive antihypertenslve alcohol deterrent hypertensive antiulcer nootropic progestogen antibacterial progestogen antisecretory antibacterial antiulcer antiemetic antiulcer intestinal antinflamm. antiinflammatory anticonvulsant antifungal nootropic bronchodiiator antithrombotic antidepressant antlbacterial immunostimulant antiasthmatic antineopiastic antiparkinsonian antihypertensive antithrombotic topical antiinflammatory anliarrhythmic topical antiinflammatory antihypertensive antineoplastic

1992 1984 1984 1990 1987 1990 1991 1985 1986 1983 1985 1986 1990 1984 1984 1986 1991 1984 1987 1989 1985 1985 1988 1990 1983 1985 1987 1988 1986 1983 1986 1988 1985 1988 1990 1987 1986 1983 1990 1983 1987 1983 1988 1991 1985 1990 1991 1992 1988 1988 1987 1984 1991 1984 1987 1988

334 321 321 305 338

305

330 330 323 321 330 323 306 321 322 324 331 322 338 316 330

330 307 306 322 331 339 307 324 322 324 307 331

308

306 339 324 322 307 322 339 323 308 331 331 307 33 1 334 308 309 340 322 332 322 340 309

m

Cumulative NCE Introduction Index, 198E-1992

GENERIC NAME piroxicarn cinnarnate plaunotol pravastatin prednicarbate progabide prornegestrone propacetarnol HCI propentofylline propionate propiverine hydrochloride propofol quazeparn quinapril quinfarnide rarnipril ranirnustine rebarnipide rernoxipride hydrochloride repirinast rifabutin rifapentine rifaxirnin rifaxirnin rilrnazafone rilrnenidine rirnantadine HCI rokitarnycin rornurtide ronafibrate rosaprostol roxatidine acetate HCI roxithrornycin rufloxacin hydrochloride RV-11

salrneterol hydroxynaphthoate sapropterin hydrochloride sargrarnostirn schizophyllan sertaconazole nitrate setastine HCI setiptiline setraline hydrochloride sevoflurane sirnvastatin sodium cellulose PO4 sofalcone sornatropin spizofurone succirner sufentanil sulbactarn sodium sulconizole nitrate sultarnycillin tosylate surnatriptan succinate suprofen surfactant TA

INDICATION

YEAR INTRODUCED ARMC VOL.. PAGE

antiinflarnrnatory antiulcer antilipidernic topical antiinflarnrnatory anticonvulsant progestogen analgesic cerebral vasodilator urologic anesthetic hypnotic antihypertensive arnebicide antihypertensive antineoplastic antiulcer antipsychotic antiallergic antibacterial antibacterial antibiotic antibiotic hypnotic antihypertensive antiviral antibiotic irnrnunostimulant hypolipidernic antiulcer antiulcer antiulcer antibacterial antibiotic bronchodilator

I988 1987 1989 1986 1985 1983 1986 1988 1992 1986 1985 1989 1984 1989 1987 1990 1990 1987 1992 1988 1985 1987 1989 1988 1987 1986 1991 1986 1985 1986 1987 1992 1989 1990

24, 23, 25, 22, 21, 19. 22, 24, 28, 22, 21, 25, 20, 25. 23, 26, 26, 23. 28, 24, 21, 23, 25, 24, 23, 22, 27, 22, 21, 22. 23, 28, 25, 26,

309 340 316 325 331 323 325 310 335 325 332 317 322 317 341 308 308 341 335 310 332 341 317 310 342 325 332 326 332 326 342 335 318 308

hyperphenylalaninemia irnrnunostirnulant irnrnunostirnulant topical antifungal antihistamine antidepressant antidepressant anesthetic hypocholesterolernic hypocalciuric antiulcer hormone antiulcer chelator analgesic 6-lactarnase inhibitor topical antifungal antibiotic antirnigraine analgesic respiratory surfactant

1992 1991 1985 1992 1987 1989 1990 1990 1988 1983 1984 1987 1987 1991 1983 1986 1985 1987 1991 1983 1987

28, 27, 22, 28, 23, 25, 26. 26, 24, 19, 20, 23, 23, 27, 19, 22, 21, 23. 27, 19, 23,

336 332 326 336 342 318 309 309 311 323 323 343 343 333 323 326 332 343 333 324 344

m

Cumulative NCE Introduction Index, 198Z-1992

GENERIC NAME

INDICATION

tazobactam sodium tazanolast teicoplanln telmesteine temafloxacin hydrochloriide temociilln disodium tenoxicam teprenone terazosin HCI terbinafine hydrochloride terconazole tertatoiol HCI thymopentin tiamenidine HCi tianeptine sodium tibolone tilisoloi hydrochloride timiperone tinazollne tioconazole tiopronln tiquizium bromide tiracizine hydrochloride tiropramide HCI tizanidlne toloxatone tolrestat toremifene tosufloxacin tosylate trientine HCI trimazosin HCI tropisetron troxipide ubenimex vesnarinone vigabatrin vinoreiblne xamoterol fumarate zaidabine zidovudine zolpldem hemitartrate zonlsamide zoplclone zuclopenthlxol acetate

O-lactamase inhibitor antlallergic antlbacterial mucoiytic antibacterial antibiotic antiinflammatory antlulcer antlhypertensive antifungal antifungal antihypertensive immunomodulator antlhypertensive antidepressant anabolic antihypertensive neuroieptic nasal decongestant antifungal urolithiasis antispasmodic antiarrhythmic antispasmodic muscle relaxant antidepressant antidiabetic antineoplastic antibacterial chelator antihypertensive antiemetic antiulcer immunostimuiant cardiostimulant anticonvulsant antineoplastic cardiotonic antiviral antiviral hypnotic anticonvulsant hypnotic antipsychotic

YEAR INTRODUCED ARMC VOL.. PAGE 1992 1990 1988 1992 1991 1984 1987 1984 1984 1991 1983 1987 1985 1988 1983 1988 1992 1984 1988 1983 1989 1984 1990 1983 1984 1984 1989 1989 1990 1986 1985 1992 1986 1987 1990 1989 1989 1988 1992 1987 1988 1989 1986 1987

28, 26, 24, 28, 27, 20, 23, 20, 20, 27, 19, 23, 21, 24, 19, 24, 28. 20, 24, 19, 25, 20, 26, 19, 20, 20, 25, 25, 26, 22, 21. 28, 22, 23, 26, 25, 25, 24, 28, 23, 24, 25, 22, 23,

336 309 311 337 334 323 344 323 323 334 324 344 333 311 324 312 337 323 312 324 318 324 310 324 324 324 319 319 310 327 333 337 327 345 310 319 320 312 338 345 313 320 327 345