Title section, list of contents, author and key word index

LIST OF CONTENTS

V O L U M E 74 N U M B E R 1 LETTERS TO NEUROSCIENCE S. Betmauni, V. H. Perry and J. L. Gordon J. A. Harris, M. Corsi, M. Quartaroli, R. Arban and M. Bentivoglio RESEARCH PAPERS S. J. Boxall, S. W. N. Thompson, A. Dray, A. H. Dickenson and L. Urban

Evidence for an early inflammatory response in the central nervous system of mice with scrapie Upregulation of spinal glutamate receptors in chronic pain

Metabotropic glutamate receptor activation contributes to nociceptive reflex activity in the rat spinal cord in vitro

13

C. Gouard~res, S. Kar and J-M. Zajac

Presence of neuropeptide FF receptors on primary afferent fibres of the rat spinal cord

21

H. Ohta, X. Li and W. T. Talman

Release of glutamate in the nucleus tractus solitarii in respinse to baroreflex activation in rats

29

R. Simantov, E. Blinder, T. Ratovitski, M. Tauber, M. Gabbay and S. Porat

Dopamine-induced apoptosis in human neuronal cells: inhibition by nucleic acids antisense to the dipamine transporter

39

E. Pettersson, M. Herrera-Marschitz, R. Rodriguez-Puertas, Z. Q. Xu, Z.-B. You, J. Hughes, R. P. Elde, U. Ungerstedt and T. H0kfelt

Evidence for aspartate-immunoreactive neurons in the neostriatum of the rat: modulation by the mesencephalic dopamine pathway via D 1-subtype of receptor

51

D. J. Holt, L. B. Hersh and C. B. Saper

Cholinergic innervation in the human striatum: a threecompartment model

67

L. F. B. Nicholson, H. J. Waldvogel and R. L. M. Faull

GABAA receptor subtype changes in the substantia nigra of the rat following quinolinate lesions in the striatum: a correlative in situ hybridization and immunohistochemical study

89

M. Robello, C. Amico, G. Bucossi, A. Cupello, M. V. Rapallino and S. Thellung

Nitric oxide and GABAA receptor function in the rat cerebral cortex and cerebellar granule cells

99

P. R. Patrylo, A. J. Kuhn, J. S. Sehweitzer and F. E. Dudek

Multiple-unit recordings during slow field-potential shifts in low-[Ca2+]o solutions in rat hippocampal and cortical slices

107

G. Leanza, O. G. Niisson, G. Nikkhah, R. G. Wiley and A. Bjiirklund

Effects of neonatal lesions of the basal forebrain cholinergic system by 192 immunoglobulin G-saporin: biochemical, behavioural and morphological characterization

119

H. K. Kin, M. J. Brisorgueil, G. Daval, X. Langlois, M. Hamon and D. Verg6

SerotoninlA receptors are expressed by a subpopulation of cholinergic neurons in the rat medial septum and diagonal band of Broca--a double immunocytochemical study

143

F. Melis, R. Stancampiano, A. Imperato, G. Carta and F. Fadda

Chronic ethanol consumption in rats: correlation between memory performance and hippocampal acetylcholine release in vitro

155

R. Schmidt-kastner, C. Wetmore and L. Olson

Comparative study of brain-derived neurotrophic factor messenger RNA and protein at the cellular level suggests multiple roles in hippocampus, striatum and cortex

161

iii

T. L. Williams, P. G. Ince, A. E. Oakley and P. J. Shaw

An immunocytochemical study of the distribution of AMPA selective glutamate receptor subunits in the normal human rooter system

185

R. Wang, L. B. MacMillan, R. T. Fremeau Jr, M. A. Magnuson, J. Lindner and L. E. Limbird

Expression of a2-adrenergic receptor subtypes in the mouse brain: evaluation of spatial and temporal information imparted by 3 kb of 5' regulatory sequence for the ~z:~AR-receptor gene in transgenic animals

199

M. Vankova, P.-A. Boyer, V. Leviel and M. Arluison

Opposite changes in the expression of enkephalin in the amygdala and hypothalamus after lesions of the bed nucleus of the stria terminalis in the rat

219

J. W. Lee and M. S. Erskine

Vaginocervical stimulation suppresses the expression of cribs induced by mating in thoracic, lumbar and sacral segments of the female rat

237

J. Bailer, M. J. Vaum and A. K. Slob

Neonatal inhibition of brain estrogen synthesis alters adult neural Fos responses to mating and pheromonal stimulation in the male rat

251

C. DellaCorte, D. Restrepo, B. Ph. M. Menco, 1. Andreini and D. L. Kalinoski

G~zq/Ga~~: immunolocalization in the olfactory epithelium of the rat (Rattus rattus) and the channel catfish (h'talurus punctatus)

261

C. D. Dunigan and A. E. Shamoo

Cation requirements of basal and ATP-regulated dopamine transport in rat pheochromocytoma cells

275

M. D. Bell, D. D. Taub and V. H. Perry

Overriding the brain's intrinsic resistance to leukocyte recruitment with intraparenchymal injections of recombinant chemokines

283

CORRIGENDUM

293

ERRATA

295

V O L U M E 74 N U M B E R 2 LETTER TO NEUROSCIENCE X. Langlois, S. El Mestikawy, M. Arpin, A. Triller, M. Hamon and M. Darmon

Differential addressing of 5-HTIAand 5-HT IB receptors in transfected LLC-PK1 epithelial cells: a model of receptor targeting in neurons

297

RESEARCH PAPERS S. C. Heinrichs, M. P. StenzeI-Poore, L. H. Gold, E. Battenberg, F. E. Bloom, G. F. Koob, W. W. Vale and E. Merlo Pich

Learning impairment in transgenic mice with central overexpression of corticotropin-releasing factor

303

K. R. Melia, A. E. Ryabinin, K. P. Corodimas, M. C. Wilson and J. E. Ledoux

Hippocampat-dependent learning and experiencedependent activation of the hippocampus are preferentially disrupted by ethanol

313

L. L. Voronin, M. Volgushev, M. Chistiakova, U. Kuhnt and W. Singer

Involvement of silent synapses in the induction of long-term potentiation and long-term depression in neocortical and hippocampal neurons

323

F. H. Brucato, E. D. Levin, D. D. Mott, D. V. Lewis, W. A. Wilson and H. S. Swartzwelder

Hippocampal long-term potentiation and spatial learning in the rat: effects of GABA B receptor blockade

331

A. Guti6rrez, Z. U. Khan, D. Ruano, C. P. Miralles, J. Vitorica and A. L. De Bias

Aging-related subunit expression changes of the GABAA receptor in the rat hippocampus

341

H. Le Jeune, D. Cecyre, W. Rowe, M. J. Meaney and R. Quirion

lonotropic glutamate receptor subtypes in the aged memory-impaired and unimpaired Long Evans rat

349

iv

K. T. Y. T.

Yamada, M. Hiramatsu, Y. Noda, Mamiya, M. Mural, T. Kameyama, Komori, T. Nikai, H. Sugihara and Nabeshima

Role of. nitric oxide and cyclic GMP in the dizocilpineinduced impairment of spontaneous alternation behavior in mice

365

A. Surkis, B. Taylor, C. S. Peskin and C. S. Leonard

Quantitative morphology of physiologically identified and intracellularly labeled neurons from the guinea-pig laterodorsal tegmental nucleus in vitro

375

H. Imon, K. Ito, L. Dauphin and R. W. McCarley

Electrical stimulation of the cholinergic laterodorsal tegmental nucleus elicits scopolamine-sensitive excitatory postsynaptic potentials in medial pontine reticular formation neurons

393

M. Jung, J. C. Michaud, R. Steinberg, M. C. Barnouin, A. Hayar, G. Mons, J. Souiihac, X. Emonds-Alt, P. Soubrie and G. Le Fur

Electrophysiological, behavioural and biochemical evidence for activation of brain noradrenergic systems following neurokinin NK 3 receptor stimulation

403

J. P. Sastre, C. Buda, K. Kitahama and M. Jouvet

Importance of the ventrolateral region of the periaqueductal gray and adjacent tegmentum in the control of paradoxical sleep as studied by muscimol microinjections in the cat

415

Y.-J. Wang, C.-L. Liu and G.-F. Tseng

Compartmentalization of calbindin and parvalbumin in different parts of rat rubrospinal neurons

427

S. K. Goldsmith and J. N. Joyce

Dopamine D2 receptors are organized in bands in normal human temporal cortex

435

U. Schmidt, C. Beyer, A. B. Oestreicher, I. Reisert, K. Schilling and C. Pilgrim

Activation of dopaminergic D l receptors morphogenesis of developing striatal neurons

promotes

453

R. J. Williams, M. Maus, N. Stella, J. Glowinski and J. Premont

Reduced glucose metabolism enhances the glutamateevoked release of arachidonic acid from striatal neurons

461

T. Obradovic, K. M. Imel and S. R. White

Methylenedioxymethamphetamine-induced inhibition of neuronal firing in the nucleus accumbens is mediated by both serotonin and dopamine

469

J.-Y. Chang, J. M. Paris, S. F. Sawyer, A. B. Kirillov and D. J. Woodward

Neuronal spike activity in rat nucleus accumbens during cocaine self-administration under different fixed-ratio schedules

483

I. M. Stanford and M. G. Lacey

Electrophysiological investigation of adenosine trisphosphate-sensitive potassium channels in the rat substantia nigra pars reticulata

499

G. M. Seigel, J. Rollins, T. R. Mhyre, T. Poles, U. Fideli and J. Holliday

Immortalized cerebellar cells can be induced to display mature neuronal characteristics

511

K. Tomizawa, H. Matsui, M. Matsushita, J. Lew, M. Tokuda, T. Itano, R. Konishi, J. H. Wang and O. Hatase

Localization and development changes in the neuronspecific cyclin-dependentkinase 5 activator (p35nckSa)in the rat brain

519

M. Duefias, I. Torres-Aleman, F. Naftolin and L. M. Garcia-Segura

Interaction of insulin-like growth factor-I and estradiol signaling pathways on hypothalamic neuronal differentiation

531

S. Weiss, O. Cataltepe and A. J. Cole

Anatomical studies of DNA fragmentation in rat brain after systemic kainate administration

541

E. Vaudano, G. Campbell and S. P. Hunt

Change in the molecular phenotype of Schwann cells upon transplantation into the central nervous system: downregulation of c-jun

553

G. Gomez, D. Restrepo, N. Rawson, L. D. Lowry, W. M. Keane and J. L. Rothstein

Induction of differentiation of human olfactory neuroblastoma cells into odorant-responsive cells

567

M. A. Gates, E. D. Laywell, H. Fillmore and D. A. Steindler

Astrocytes and extracellular matrix following intracerebral transplantation of embryonic ventral mesencephalon or lateral ganglionic eminence

579

M. K. Matyszak and V . H . Perry

The potential role of dendritic cells in immune-mediated inflammatory diseases in the central nervous system

599

M. Kress, J. R6dl and P. W. Reeh

Stable analogues of cyclic AMP but not cyclic GMP sensitize unmyelinated primary afferents in rat skin to heat stimulation but not to inflammatory mediators, in vitro

609

Dorsal rhizotomy induces transient expression of the highly sialylated isoform of the neural cell adhesion molecule in neurons and astrocytes of the adult rat spinal cord

619

Global and serial neurons lbrm a hierarchically arranged interface proposed to underlie memory and cognition

625

Glutamate hyperexcitability and seizure-like activity throughout the brain and spinal cord upon relief from chronic glutamate receptor blockade in culture

653

N. A. Simonian, R. L. Getz, J. C. Leveque, C. Konradi and J. T. Coyle

Kainate induces apoptosis in neurons

675

J. N. Armstrong, J.-C. L. Plumier, H. A. Robertson and R. W. Currie

The inducible 70,000 molecular weight heat shock protein is expressed in the degenerating dentate hilus and piriform cortex after systemic administration of kainic acid in the rat

685

D. G. Fujikawa, J. S. Kim, A. H. Daniels, A. F. Alcaraz and T. B. Sohn

hi vivo elevation of extracellular potassium in the rat amygdala increases extracellular glutamate and aspartate and damages neurons

695

B. A. Bahr, K. B. Hoffman, M. Kessler, M. Hennegriff, G. Y. Park, R. S. Yamamoto, B. T. Kawasaki, P. W. Vanderklish, R. A. Hall and G. Lynch

Distinct distributions of a-amino-3-hydroxy-5-methyl-4isoxazolepropionate (AMPA) receptor subunits and a related 53.000 M R antigen (GR53) in brain tissue

707

D. Manahan-Vaughan and K. G. Reymann

Metabotropic glutamate receptor subtype agonists facilitate long-term potentiation within a distinct time window in the dentate gyrus in vivo

723

H. Kuo, D. K. Ingram, L. C. Walker, M. Tian, J. M. Hengemihle and M. Jucker

Similarities in the age-related hippocampal deposition of periodic acid-Schiff-positive granules in the senescenceaccelerated mouse P8 and C57BL/6 mouse strains

733

M. M. Nicolle, J. L. Bizon and M. Gallagher

In vitro autoradiography of ionotropic glutamate receptors in hippocampus and striatum of aged Long-Evans rats: relationship to spatial learning

741

J. E. Kerr, S. G. Beck and R. J. Handa

Androgens selectively modulate c-jos messenger RNA induction in the rat hippocampus following novelty

757

G. P. Mark, P. V. Rada and T. J. Shors

Inescapable stress enhances extracellular acetylcholine in the rat hippocampus and prefrontal cortex but not the nucleus accumbens or amygdala

767

J. E. Brecknell, J. S. Du, E. Muir, P. S. Fidler, M. L. Hlavin, S. B. Dunnett and J. W. Fawcett

Bridge gralis of fibroblast growth factor-4-secreting Schwannoma cells promote functional axonal regeneration in the nigrostriatal pathway of the adult rat

775

VOLUME

74 N U M B E R

3

LETTER TO N E U R O S C I E N C E L. Bonfanti, A. Merighi and D. T. Theodosis

COMMENTARY N. J. Woolf

RESEARCH PAPERS A. N. van den Pol, K. Obrietan and A. Belousov

N. B. Mereuri, P. Grillner and G. Bernardi

N-Methyl-D-aspartate receptors mediate a slow excitatory postsynaptic potential in the rat midbrain dopaminergic neurons

785

Z.-B. You, M. Herrera-Marschitz, E. Pettersson, I. Nylander, M. Goiny, H.-Z. Shou, J. Kehr, O. Godukhin, T. Hiikfelt, L. Terenius and U. Ungerstedt

Modulation of neurotransmitter release by cholecystokinin in the neostriatum and substantia nigra of the rat: regional and receptor specificity

793

J. S. Brog and D. S. Zahm

Morphologically distinct subpopulations of neurotensinimmunoreactive striatal neurons observed in rat following dopamine depletions and D 2 receptor blockade project to the globus pallidus

805

J. Drago, C. R. Gerfen, H. Westphal and H. Steiner

D1 dopamine receptor-deficient mouse: cocaine-induced regulation of immediate-early gene and substance P expression in the striatum

813

K. Funa, N. Yamada, G. Brodin, K. Pietz, A. Ahgren, K. Wictorin, O. Lindvall and P. Odin

Enhanced synthesis of platelet-derived growth factor following injury induced by 6-hydroxydopamine in rat brain

825

J. E. Cheun and H. H. Yeh

Noradrenergic potentiation of cerebellar Purkinje cell responses to GABA: cyclic AMP as intracellular intermediary

835

M. Taoka, S.-Y. Song, M. Kubota, A. Minegishi, T. Yamakuni and S. Konishi

Increased level of neurokinin-1 tachykinin receptor gene expression during early postnatal development of rat brain

845

Z. Z. Pan and H. L. Fields

Endogenous opioid-mediated inhibition of putative painmodulating neurons in rat rostral ventromedial medulla

855

S. M. Roychowdhury and H. L. Fields

Endogenous opioids acting at a medullary g-opioid receptor contribute to the behavioral antinociception produced by GABA antagonism in the midbrain periaqueductal gray

863

R. J. Traub, J. N. Sengupta and G. F. Gebhart

Differential c-Fos expression in the nucleus of the solitary tract and spinal cord following noxious gastric distention in the rat

873

P. Duchamp-Viret, B. Palouzier-Paulignan and A. Duchamp

Odor coding properties of frog olfactory cortical neurons

885

C. B. Rozanov and M. B. Dratman

lmmunohistochemical mapping of brain triiodothyronine reveals prominent localization in central noradrenergic systems

897

S. Breen, S. Rees and D. Walker

The development of diurnal rhythmicity suprachiasmatic neurons as demonstrated immunohistochemistry

in fetal by Fos

917

A. Fergus, Y. Jin, Q.-A. Thai, N. F. Kassell and K. S. Lee

Tonic protein kinase C-mediated vascoconstriction is unmasked when nitric oxide synthase is inhibited in cerebral microvessels

927

H. A. J. M. Kurvers, G. J. Tangelder, J. G. R. de Mey, D. W. Slaaf, F. A. J. M. van den Wildenberg, P. 3. E. H. M. Kitslaar, R. S. Reneman, E. V. Rouwet and M. J. H. M. Jacobs

Skin blood flow disturbances in the contralateral limb in a peripheral mononeuropathy in the rat

935

Endogenous brain-derived neurotrophic factor is anterogradely transported in primary sensory neurons

945

V O L U M E 74 N U M B E R 4 LETTERS TO NEUROSCIENCE X.-F. Zhou and R. A. Rush

vii

Glutamate receptors in spinal motoneurons after sciatic nerve transection

953

DARPP-32-rich zones in grafts of lateral ganglionic eminence govern the extent of functional recovery in skilled paw reaching in an animal model of Huntington's disease

959

P. Barn~oud, M. Mazadier, J.-M. Miquet, S. Parmentier, P. Dub~dat, A. Doble and A. Boireau

Neuroprotective effects of riluzole on Parkinson's disease in the rat

of

971

S. Wolfarth, J. Konieczny, M. Smia|owska, G. Schulze and K. Ossowska

Influence of 6-hydroxydopamine lesion of the dopaminergic nigrostriatal pathway on the muscle tone and electromyographic activity measured during passive movements

985

L. Stefanis and R. E. Burke

Transneuronal degeneration in substantia nigra pars reticulata following striatal excitotoxic injury in adult rat: time-course, distribution and morphology of cell death

997

J. Deuchars and A. M. Thomson

CA I pyramid pyramid connections in rat hippocampus in vitro: dual intracellular recordings with biocytin filling

1009

A. M. Aloisi, M. E. Albonetti and G. Carli

Formalin-induced changes in adrenocorticotropic hormone and corticosterone plasma levels and hippocampal choline acetyltransferase activity in male and female rats

1019

J. Sirvio, J. Larson, C. N. Quach, G. A. Rogers and G. Lynch

Effects of pharmacologically facilitating glutamatergic transmission in the trisynaptic intrahippocampal circuit

1025

A. Gasbarri, A. Sulli, R. lnnocenzi, C. Pacitti and J. D. Brioni

Spatial memory impairment induced by lesion of the mesohippocampal dopaminergic system in the rat

1037

G. Magowan and D. J. Price

Trophic and outgrowth-promoting effects of K+-induced depolarization on developing thalamic cells in organotypic culture

1045

H. Wang and J. F. Morris

Presence of neuronal nitric oxide synthase in the suprachiasmatic nuclei of mouse and rat

1059

Z. Zuo, J. De Vente and R. A. Johns

Halothane and isoflurane dose-dependently inhibit the cyclic GMP increase caused by N-methyl-D-aspartate in rat cerebellum: novel localization and quantitation by in vitro autoradiography

1069

B. D. Grubb, R. C. Riley, P. J. Hope, L. Pubols and A. W. Duggan

The burst-like firing of spinal neurons in rats with peripheral inflammation is reduced by an antagonist of N-methylD-aspartate

1077

B. Lu, A. J. Czernik, S. Popov, T. Wang, M.-M. Poo and P. Greengard

Expression of synapsin I correlates with maturation of the neuromuscular synapse

1087

Y.-Z. Zhang, J. Hannibal, Q. Zhao, K. Moiler, N. Danielsen, J. Fahrenkrug and F. Sundler

Pituitary adenylate cyclase activating peptide expression in the rat dorsal root ganglia: up-regulation after peripheral nerve injur?

1099

C. L. Stueky, S. A. Thayer and V. S. Seyboid

P r o s t a g l a n d i n E 2 increases the proportion of neonatal rat dorsal root ganglion neurons that respond to bradykinin

1111

Y. Kawakami and T. Oshima

Long-lasting potentiation in the secondary somatosensory cortex affects motor control: assessment by H-reflex

1125

W. L6scher, A. Richter, G. Nikkhah, C. Rosenthal, U. Ebert and H.-J. Hedrich

Behavioural and neurochemical dysfunction in the circling (ci) rat: a novel genetic animal model of a movement disorder

1135

A. Popratiloff, V. N. Kharazia, R. J. Weinberg, B. Laonipon and A. Rustioni R E S E A R C H PAPERS N. Nakao, E. M. Grasbon-Frodl, H. Widner and P. Brundin

viii

a

model

P. E. Hughes, T. Alexi, T. Yoshida, S. S. Sehreiber and B. Knusel

Excitotoxic lesion of rat brain with quinolinic acid induces expression of p53 messenger RNA and protein and p53inducible genes Bax and Gadd-45 in brain areas showing DNA fragmentation

1143

A. H. Cohen, L. Guan, J. Harris, R. Jung and T. Kiemel

Interaction between the caudal brainstem and the lamprey central pattern generator for locomotion

1161

L. D. Matzel, R. F. Rogers and A. C. Talk

Bidirectional regulation of neuronal potassium currents by the G-protein activator aluminium fluoride as a function of intracellular calcium concentration

1175

B. F. King, J. T. Neary, Q. Zhu, S. Wang, M. D. Norenberg and G. Burnstock

P2 purinoceptors in rat cortical astrocytes: expression,

1187

D. H. Lowenstein and L. Arsenault

Dentate granule cell layer collagen explant cultures: spontaneous axonal growth and induction by brain-derived neurotrophic factor or basic fibroblast growth factor

1197

Y. Kawamoto, S. Nakamura, S. Nakano, N. Oka, I. Akiguchi and J. Kimura

Immunohistochemical localization of brain-derived neurotrophic factor in adult rat brain

1209

calcium-imaging and signalling studies

AUTHOR INDEX

]~hgren, A. 825 Akiguchi, 1. 1209 Albonetti, M. E. 1019 Alcaraz, A. F. 695 Alexi, T. 1143 Aloisi, A. M. 1019 Amico, C. 99 Andreini, I. 261 Arban, R. 7 Arluison, M. 219 Armstrong, J. N. 685 Arpin, M. 297 Arsenault, L. 1197 Bahr, B. A. 707 Bakker, J. 251 Barn6oud, P. 971 Barnouin, M. C. 403 Battenburg, E. 303 Baum, M. J. 251 Beck, S. G. 757 Bell, M. D. 283 Belousov, A. 653 Bentivoglio, M. 7 Bernardi, G. 785 Betmouni, S. 1 Beyer, C. 453 Bizon, J. L. 741 Bj6rklund, A. 119 Blinder, E. 39 Bloom, F. E. 303 Boireau, A. 971 Bonfanti, L. 619 Boxall, S. J. 13 Boyer, P.-A. 219 Brecknell, J. E. 775 Breen, S. 917 Brioni, J. D. 1037 Brisorgueil, M. J. 143 Brodin, G. 825 Brog, J. S. 805 Brucato, F. H. 331 Brundin, P. 959 Bucossi, G. 99 Buda, C. 415 Burke, R. E. 997 Burnstock, G. 1187

Dauphin, L. 393 Davak G. 143 de Mey, J. G. R. 935 De Blas, A. L. 341 De Vente, J. 1069 DellaCorte, C. 261 Deuchars, J. 1009 Dickenson. A. H. 13 Doble, A. 971 Drago, J. 813 Dratman, M. B. 897 Dray, A. 13 Du, J. S. 775 Dub6dat, P. 971 Duchamp, A. 885 Duchamp-Viret, P. 885 Dudek, F. E. 107 Duefias, M. 531 Duggan, A. W. 1077 Dunigan, C. D. 275 Dunnett, S. B. 775

Hannibal, J. 1099 Harris, J. 1161 Harris, J. A. 7 Hatase, O. 519 Hayar, A. 403 Hedrich, H.-J. 1135 Heinrichs, S. C. 303 Hengemihle, J. M. 733 Hennegriff, M. 707 Herrera-Marschitz, M. 51,793 Hersh, L. B. 67 Hiramatsu, M. 365 Hlavin, M. L. 775 Hoffman, K. B. 707 H6kfelt, T. 51, 793 Holliday, J. 511 Holt, D. J. 67 Hope, P. J. 1077 Hughes, J. 51 Hughes, P. E. 1143 Hunt, S. P. 553

Ebert. U. 1135 E1 Mestikawy, S. 297 Elde, R. P. 51 Emonds-Alt, X. 403 Erskine, M. S. 237

Imel, K. M. 469 Imon, H. 393 lmperato, A. 155 lnce, P. G. 185 lngram, D. K. 733 Innocenzi, R. 1037 ltano, T. 519 lto, K. 393

Fadda. F:. 155 Fahrenkrug, J. 1099 Faull, R. L. M. 89 Fawcett, J. W. 775 Fergus, A. 927 Fideli, U. 511 Fidler, P. S. 775 Fields, H. L. 855 Fields, H. L. 863 Fillmore, H. 579 Fremeau, R. T. Jr 199 Fujikawa. D. G. 695 Funa, K. 825

Campbell, G. 553 Carli, G. 1019 Carta, G. 155 Cataltepe, O. 541 Cecyre, D. 349 Chang, J.-Y. 469 Cheun, J. E. 835 Chistiakova, M. 323 Cohen, A. H. 1161 Cole, A. J. 541 Corodimas, K. P. 313 Corsi, M. 7 Coyle, J. T. 675 Cupello, A. 99 Currie, R. W. 685 Czernik, A. J. 1087

Gabbay, M. 39 Gallagher, M. 741 Garcia-Segura, L. M. 531 Gasbarri, A. 1037 Gates, M. A. 579 Gebhart, G. F. 873 Gerfen, C. R. 813 Getz, R. k. 675 Glowinski, J. 461 Godukhin, O. 793 Goiny, M. 793 Gold, L. H. 303 Goldsmith, S. K. 435 Gomez. G. 567 Gordon, J. L. I Gouardbres. C. 21 Grashon-Frodl, E. M. 959 Greengard, P. 1087 Grillner, P. 785 Grubb, B. D. 1077 G u a m L. 1161 Guti~rrez, A. 341

Daniels, A. H. 695 Danielsen, N. 1099 Darmon, M. 297

Hall. R. A. 71)7 Hamon, M. 143, 297 Handa, R. J. 757

Jacobs, M. J. H. M. 935 Jim Y. 927 Johns, R. A. 1069 Jouvet, M. 415 Joyce, J. N. 435 Jucker, M. 733 Jung, R. 1161 Jung, M. 403 Kalinoski, D. L. 261 Kameyama, T. 365 Kar, S. 21 Kassell, N. F. 927 Kawakami, Y. 1125 Kawamoto, Y. 1209 Kawasaki, B. T. 707 Keane, W. M. 567 Kehr, J. 793 Kerr, J. E. 757 Kessler, M. 707 Khan, Z. U. 341 Kharazia, V. N. 953 Kia, H. K. 143 Kiemel. T. 1161 Kim, J. S. 695 Kimura J. 1209 King, B. F. 1187 Kirillov A. B. 469 Kitahama, K. 415 Kitslaar P. J. E. H. M. 935 Knusel, B. 1143 Komori Y. 365 Konieczny, J. 985 Konishi R. 519 Konishi, S. 845 Konradi, C. 675 Koob, G. F. 303

Kress, M. 609 Kubota, M. 845 Kuhn, A. J. 107 Kuhnt, U. 323 Kuo, H. 733 Kurvers, H. A. J. M. 935 Lacey, M. G. 469 Langlois, X. 143 Langlois, X. 297 Laonipon, B. 953 Larson, J. 1025 Laywell, E. D. 579 Le Fur, G. 403 Le Jeune, H. 349 Leanza, G. 119 Ledoux, J. E. 313 Lee, J. W. 237 Lee, K. S. 927 Leonard, C. S. 375 Leveque, J. C. 675 Leviel, V. 219 Levin, E. D. 331 Lew, J. 519 Lewis, D. V. 331 Li, X. 29 Limbird, L. E. 199 Lindner, J. 199 Lindvall, O. 825 Liu, C.-L. 427 L6scher, W. 1135 Lowenstein, D. H. 1197 Lowry, L. D. 567 Lu, B. 1087 Lynch, G. 707, 1025 MacMillan, L. B. 199 Magnuson, M. A. 199 Magowan, G. 1045 Mamiya, T. 365 Manahan-Vaughan, D. 723 Mark, G. P. 767 Matsui, H. 519 Matsushita, M. 519 Matyszak, M. K. 599 Matzel, L. D. 1175 Maus, M. 461 Mazadier, M. 971 McCarley, R. W. 393 Meaney, M. J. 349 Melia, K. R. 313 Melis, F. 155 Menco, B. Ph. M. 261 Mercuri, N. B. 785 Merighi, A. 619 Merlo Pich, E. 303 Mhyre, T. R. 511 Michaud, J. C. 403 Minegishi, A. 845 Miquet, J.-M. 971 Miralles, C. P. 341 Moiler, K. 1099 Mons, G. 403 Morris, J. F. 1059 Mott, D. D. 331 Muir, E. 775 Murai, M. 365 Nabeshima, T. 365 Naftolin, F. 531 Nakamura, S. 1209 Nakano, S. 1209

Nakao, N. 959 Neary, J. T. 1187 Nicholson, L. F. B. 89 Nicolle, M. M. 741 Nikai, T. 365 Nikkhah, G. 119, 1135 Nilsson, O. G. 119 Noda, Y. 365 Norenberg, M. D. 1187 Nylander, I. 793 Oakley, A. E. 185 Obradovic, T. 469 Obrietan, K. 653 Odin, P. 825 Oestreicher, A. B. 453 Ohta, H. 29 Oka, N. 1209 Olson, L. 161 Oshima, T. 1125 Ossowska, K. 985 Pacitti, C. 1037 Palouzier-Paulignan, B. 885 Pan, Z. Z. 855 Paris, J. M. 469 Park, G. Y. 707 Parmentier, S. 971 Patrylo, P. R. 107 Perry, V. H. 1,283, 599 Peskin, C. S. 375 Petterson, E. 51 Pettersson, E. 793 Pietz, K. 825 Pilgrim, C. 453 Plumier, J.-C, L. 685 Poles, T. 511 Poo, M.-M. 1087 Popov, S. 1087 Popratiloff, A. 953 Porat, S. 39 Premont, J. 461 Price, D. J. 1045 Pubols, L. 1077 Quach, C. N. 1025 Quartaroli, M. 7 Quirion, R. 349 Rada, P. V. 767 Rapallino, M. V. 99 Ratovitski, T. 39 Rawson, N. 567 Reeh, P. W. 609 Rees, S. 917 Reisert, I. 453 Reneman, R. S. 935 Restrepo, D. 261,567 Reymann, K. G. 723 Richter, A. 1135 Riley, R. C. 1077 Robello, M. 99 Robertson, H. A. 685 R6dl, R. 609 Rodriguez-Puertas, R. 51 Rogers, G. A. 1025 Rogers, R. F. 1175 Rollins, J. 511 Rosenthal, C. 1135 Rothstein, J. L. 567 Rouwet, E. V. 935 Rowe, W. 349 xi

Roychowdhury, S. M. 863 Rozanov, C. B. 897 Ruano, D. 341 Rush, R. A. 945 Rustioni, A. 953 Ryabinin, A. E. 313

Saper, C. B. 67 Sastre, J. P. 415 Sawyer, S. F. 469 Schilling, K. 453 Schmidt, U. 453 Schmidt-Kastner, R. 161 Schreiber, S. S. 1143 Schule, G. 985 Schweitzer, J. S. 107 Seigel, G. M. 511 Sengupta, J. N. 873 Seybold, V. S. 1111 Shamoo, A. E. 275 Shaw, P. J. 185 Shors, T. J. 767 Shou, H.-Z. 793 Simantov, R. 39 Simonian, N. A. 675 Singer, W. 323 Sirvio, J. 1025 Slaaf, D. W. 935 Slob, A. K. 251 Smiatowska, M. 985 Sohn, T. B. 695 Song, S.-Y. 845 Soubrie, P. 403 Souilhac, J. 403 Stancampiano, R. 155 Stanford, I. M. 469 Stefanis, L. 997 Steinberg, R. 403 Steindler, D. A. 579 Steiner, H. 813 Stella, N. 461 Stenzel-Poore, M. P. 303 Stucky, C. L. 1111 Sugihara, H. 365 Sulli, A. 1037 Sundler, F. 1099 Surkis, A. 375 Swartzwelder, H. S. 331

Talk, A. C. 1175 Talman, W. T. 29 Tangelder, G. J. 935 Taoka, M. 845 Taub, D. D. 283 Tauber, M. 39 Taylor, B. 375 Terenius, L. 793 Thai, Q.-A. 927 Thayer, S. A. 1111 Thellung, S. 99 Theodosis, D. T. 619 Thompson, S. W. N. 13 Thomson, A. M. 1009 Tian, M. 733 Tokuda, M. 519 Tomizawa, K. 519 Torres-Aleman, I. 531 Traub, R. J. 873 Triller, A. 297 Tseng, G.-F. 427

Ungerstedt, U. 51,793 Urban, L. 13 Vale, W. W. 303 van den Pot, A. N. 653 van den Wildenberg, F. A. J. M. 935 Vanderklish, P. W. 707 Vankova, M. 219 Vaudano, E. 553 Verg6, D. 143 Vitorica, J. 341 Volgushev, M. 323 Voronin, L. L. 323 Waldvogel, H. J. 89 Walker, D. 917 Walker, L. C. 733 Wang, H. 1059 Wang, J. H. 519

Wang, R. 199 Wang, S. 1187 Wang, T. 1087 Wang, Y.-J. 427 Weinburg, R. J. 953 Weiss, S. 541 Westphal, H. 813 Wetmore, C. 161 White, S. R. 469 Wictorin, K. 825 Widner, H. 959 Wiley, R. G. 119 Williams, R. J. 461 Williams, T. L. 185 Wilson, M. C. 313 Wilson, W. A. 331 Wolfarth, S. 985 Woodward, D. J. 469 Woolf, N. J. 625

xii

Xu, Z. Q. 51 Yamada, K. 365 Yamada, N. 825 Yamakuni, T. 845 Yamamoto, R. S. 707 Yeh, H. H. 835 Yoshida, T. 1143 You, Z.-B. 51,793 Zahm, D. S. 805 Zajac, J-M. 21 Zhang, Y.-Z, 1099 Zhao, Q. 1099 Zhou, X.-F. 945 Zhu, Q. 1187 Zuo, Z. 1069

KEY W O R D INDEX ct-adrenergic receptor 403 ct-phenyl-tert-butyl nitrone 959 ch-adrenergic receptor subtypes 199 acetylcholine 67, 393, 625 acetylcholine release 155, 767 activity-dependent facilitation 1175 addressing 297 afterdischarges 1077 aging 341,349, 733 alcohol 313 Alzheimer's disease 519, 733 amino acids 793 AMPA 7, 349, 741,953 AMPA receptor 1025 AMPA-binding protein 707 amphetamine 813 amyotropic lateral sclerosis 185 analgesia 237, 855 androgen receptor 757 antergrade transport 945 antibody 341 anti-peptide antibody 1209 apoptosis 541, 1143 arachidonic acid 461 aspartate 29 astrocytes 733, 1187 astroglia 953 ATP 1187 auditory cortex 435 axonal 427 axonal regeneration 775 axotomy 21,953

cell culture 511,567 cell death 39, 675, 685, 695, 997 central nervous system 1209 cerebellar granule cells 675 cerebral cortex 845 CGP 46381 331 chemokines 283 chlordiazepoxide 303 cholecystokinin 793 choline acetyltransferase 1019 cholinergic 375, 393 cholinergic system 143 chondroitin sulfate proteoglycans 579 chronic ethanol 155 chronic constriction injury 935 circadian rhythms 917 circadian regulation 1059 circling rat 1135 CNS regeneration 553 CNS 599 cocaine 483 competitive RT-PCR 845 context 313 contralateral extremity 935 cortical column 435 CTOP 863 cyclic AMP 835 cyclic GMP 365 cyclic nucleotides 609 cyclin 519 cyclin-dependent kinase 519

basal ganglia 51, 67, 805 bcl-2 1143 BDNF 161,825 bed nucleus of the stria terminalis 219 behavior 483 behavioural recovery 959 benzodiazepine receptor 341 bicarbonate buffer 275 bicuculline 863, 855 blobs 435 blood-brain barrier 283 bouton 1009 bradykinin 1111 brain 1069 brain imaging 897 brain maturation 519 brain grafts 579 brain slice 499 brainstem 393 bursts 1077

Dl agonists 51 D~- and D2-1ike receptors 453 delayed-type hypersensitivity 599 dendrite 375, 1009 dendritic cells 599 dentate gyrus 1197 development 653 DHPG 723 differentiation 453 dizocilpine 365 DNA fragmentation 541 dopamine 453, 469, 793, 1135 dopaminergic metabolism 971 dopaminergic neuron 825 dopaminergic neurons 579, 785 dorsal horn 7 dorsal root 1111 dorsal root ganglia 1099 dot blotting 1209 drug abuse 469 drug of abuse 483 dynorphin 51,793, 813

c-fos 453, 757, 813

electromyogram 985 electron microscopy 1009 electrophysiology 483, 885 emotionality 303 endogenous opioid 855 enkephalin 813 enzyme-linked immunosorbent assay 825 epilepsy 685 estrogen receptor 531 excitatory amino acids 51,707 excitatory postsynaptic potential 785, 1009 excitotoxicity 675, 997 experimental allergic encephalomyelitis 599 explant cultures 1197

c-fos 313 c-Fos 1125 c-Jun 757 Ca 2÷ 107 cable model 375 calbindin 427 calcium 567, 1175 CaM kinase II 927 cancer 567 capsaicin dorsal rhizotomy 21 cat 415 catecholamines 199 caudate 67 xiii

lateral/basolateral amygdaloid complex 219 learning 625 learning and memory 365 lemakalim 499 lesion 619, 825 leukocyte recruitment 283 light signal transmission 1059 limbic 435, 685 LLC-PK1 epithelial cells 297 locus coeruleus 897 long-term depression 323 long-lasting potentiation 1125 long-term potentiation 323. 331 loose ligation 7 low-affinity NGF receptor rat 119

lear conditioning 313 fetus 917 fibrolast growth factor-4 775 fluoride 1175 Fos immunoreactivity 251 frequency facilitation 1025 frog 885 G-proteins 261, 1175 Gall 261 GI/q 261 GABA 331,415,499, 653, 835, 1025 GABA A receptor 89. 99. 341 ganglion neurons 1111 gender differences 1019 gene expression 1143 gene regulation 553 gerbil 403 glia 553, 579 globus pallidus 805 glucose 461 GIuR antibodies 707 glutamate 29, 51,461,625, 1025 glutamate toxicity 511 glutamine 695 graft survival 959 growth factors 567, 1197 guanylyl cyclase 1069 guinea-pig 403

magnesium 275 MAP kinase 1187 mating 237 MCPG 723 MDMA 469 mechanomyogram 985 medial entorhinal cortex 107 memory 303, 313. 331 memory encoding 625 metabotropic glutamate receptor 13, 723 [Met]enkephalin 219 microcirculation 927 microdialysis 29, 767, 793 microglia 1 microtubute-associated protein-2 531 MIP-2 283 model cell line 567 modulation 835 monoamines 625 Morris water maze 1037 motoneuron activity 1125 motor neuron 185 motor systems 1161 mouse 1045 movement disorders 1135 mRNA 341 muscimol 415 muscle tone 985

H-reflex 1125 heat shock 685 heparan sulfate proteoglycan 733 Hermissenda 1175 high potassium 695 hippocampus 107, 155. 283. 303, 323, 331, 435. 685. 723. 733. 757, 845, 1019. 1025. 1197 5-HTIA 297 5-HT~ receptors 297 Huntington's disease 997 6-hydroxdopamine 971,985. 1037 hyperalgesia 7, 609 hypersomnia 415 hypothalamus 653, 917

N-CAM 619 N-methyl-D-aspartate 349. 365, 653, 785, 1009 Na' 275 NADPH-diaphorase 1059 naloxone 855. 863 naltrexone 863 neocortex 323 neonatal ATD treatment 251 nerve block 935 nerve injury 945. 1099 nerve-muscle co-culture 1087 neural activity 1045 neural oscillator 1161 neural plasticity 625 neurite growth 1045 neuritotrophic action 453 neurodegeneration 39, 733 neuronal depolarization 695 neuronal survival 531 neurons 461 neuropeptide 813 neuropeptide FF 21 neuropeptides 1099 neuroprotection 971 neurotransmitters 897 neurotrophic factor 945 neurotrophin 1209 neurotrophins 1197

ibotenic acid lesions 219 ICI 182,780 531 immediate early gene 917 immunoabsorption 897 lmmunocytochemistry 1. 143, 261, 511, 1059 lmmunohistochemistry 16t. 219, 619, 825. 1209 lmmunotoxin 119 inflammation I, 283 inflammatory diseases 599 inhalational anesthetics 1069 inhibitory avoidance 1037 m situ nick translation 541 tn situ hybridization 161, 199. 219 mtracellular Ca 2+ 1187 intracellular tetanization 323 m vitro 13

lonotropic excitatory amino acid receptors 349 Jun-B 757 K+-ATPase 275 K+-induced depolarization 1045 kainate 349, 541,653, 741 kinetics 275 lactate 461 laminin 1087 xiv

N~-nitro-L-arginine methyl ester 365 nitric oxide 99, 365, 927, 1069 nitric oxide synthase 375, 927, 1069 NMDA 741,953 NMDA receptors 1077 nociception 873 nociceptor 609 non-NMDA 185 norepinephrine 835 nucleotide 1187 nucleus accumbens 469, 483 nucleus basalis 119 nucleus tractus solitarii 29

sciatic nerve 7 scrapie 1 second messengers 609 secondary somatosensory cortex 1125 seizures 541 selective vulnerability 185 senktide 403 sensitization 609, 1111 sensory neurons 945 sensory coding 885 sensory neurons 1099 septum 119, 143 serotonin 469 serotoninergic system 143 sex steroids 531 sexual behavior 251 short-term potentiation 723 silent synapses 323 skilled paw use 971 skin blood flow 935 sodium 275 somadendritic 4, 27 spatial learning 741 spatial memory 349 spectrogram 1161 spinal cord 13, 21,237, 619, 653, 945, 1099, 1161 spinal neurons 1077, 1087 spontaneous synaptic currents 1087 SR 142801 403 status epilepticus 541 stress 303 striatum 453, 461,805, 959, 997 striosome 67 substance P 845, 1111 substantia nigra 89, 775, 785, 997, 1037 substantia nigra lesion 985 sympathetic afferent 873 sympathetic nervous system 897 synapse 1009 synaptic current 499 synaptophysin 1087 synaptosomes 707

odor 885 olfaction 261,567, 885 olfactory cortex 885 ontogeny 917 organotypic cultures 1045 ouabain 275 P2 purinoceptor 1187 PACAP 1099 pain 609, 873, 1019 pain modulation 855 paradoxical sleep 415 parasympathetic afferent 873 Parkinson's disease 39, 985, 1135 parvalbumin 427 peptide regulation 805 peptides 805 perforant path 1025 periaqueductal gray 415 peripheral inflammation 1077 peripheral injury 953 peripheral nerve graft 553 pheromonal stimulation 251 5-phosphonovalerate (APV) 785 piriform cortex 685 plasticity 519, 1197 polysialic acid 619 potassium currents 1175 preoptic area 251 preproenkephalin A 219 programmed cell death 1143 prostalglandin E z 1111 protein kinase C 927 protein kinase G 99 Purkinje cell 835 putamen 67

T-cells 1 tachykinin receptor 845 tachykinin receptor gene expression 845 tail-shock 767 tau protein 519 taurine 695 tenascin 579 thalamus 1045 thyroid hormones 897 tolbutamide 499 trans-ADA 723 transgenic mice 199 transplantation 553 transporter 39 trophic factors 531

quinolinate lesion 89 quinolinc acid 959 rapid eye movement sleep 375 rat 89, 107, 161,427, 483, 793, 825, 971 rat brain 99, 143, 341 rat cerebellum 835 rats 935 receptor autoradiography 21 reflex sympathetic dystrophy 935 regulation of cell-specific mRNA expression 199 regulation of temporal expression 199 REM sleep 393 restraint stress 767 retrorubral field 1037 rostral ventromedial medulla 855 rostroventromedial medulla 863 rotation 971 rubrospinal neurons 427

vaginocervical stimulation 237 varicosity 375 ventral root potential 13 ventral striatum 469 ventral tegrnental area 785, 1037 ventromedial hypothalamic nucleus 219 visceral 873 water maze 741 western blotting 1209 whole-cell patch clamp 499

zif268 813

Schwann cells 775 schwannoma 775

zif 268 757 XV