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Academy of Pharmaceutical Sciences
Academy of Pharmaceutical Sciences The APhA Academy of Pharmaceutical Sciences met during the 121st Annual Meeting of the APhA in Chicago, conducting a program of valuable and well-attended symposia in addition to its organizational business sessions. The annual Academy luncheon was held on Wednesday, August 7, with honored guest APhA Board Chairman William F. Appel attending. The 1974 Ebert Prize was awarded to Jacob L. Varsano with Seymour G. Gilbert receiving a Certificate of Honorable Mention for his contribution to their winning article, "Evaluation of Interactions Between Polymers and Low Molecular Weight Compounds by GLC II: Thermodynamics and Elucidation" which was published in the January 1973 issue of the Journal ofPharmaceutical Sciences. Gordon L. Flynn, chairman of the Ebert Prize Committee, made the presentations. Additionally, 25 newly elected Academy Fellows were honored by their colleagues at the Academy luncheon. Dale E. Wurster, incoming president-elect of the Academy, served as toastmaster for the occasion. Luncheon activities included the presentation to Norman Farnsworth of the 1974 APhA Foundation-Academy of Pharmaceutical Sciences Research Achievement Award in Natural Products (sponsored by the FMC Corporation, Avicel Department). Karl Folkers was presented the 1974 APhA Foundation-Academy of Pharmaceutical Sciences Research Achievement Award in Pharmaceutical and Medicinal Chemistry (sponsored by the Upjohn Company). The luncheon address, delivered by incoming Academy President Louis Busse, expressed his optimism about the potential harmonious relationship between the Academy and APhA. He spoke of the constructive efforts which the Academy must increase if it is to better contribute new scientific advances to the profession. Emphasis was made on the need for the Academy to increase its response .:apabilities by initiating task forces of experts to develop scientific suggestions on professional issues and problems. In asking "Pharmaceutical science-is anybody listening ?" Dr. Busse pointed out that organized pharmacy must work more closely with its scientific resources if the profession is to properly increase its competence and contribution to better public health. The Academy's annual business meet458
New officers of the Academy ofPharmaceutical Sciences are (from the left) William F. McGhan , executive secretary; James C. Boylan, vice president; Louis W. Busse, president; Dale E. Wurster, president-elect, and George H. Schneller, immediate past president.
ing followed the luncheon on August 7. President George H. Schneller presented his report to the membership, and also received the reports of the Academy committee chairmen. New officers of the Academy were installed-Louis W. Busse, president; Dale E. Wurster, president-elect; James C. Boylan, vice president; George H. Schneller, past president, and Patrick P. DeLuca, member-at-Iarge. Continuing members-atlarge on the executive committee are Arnold D. Marcus and George Zografi. The sections of the Academy sponsored 37 scientific sessions, and over 230 papers, coordinated through the Academy Program Committee, John Poole, chairman. Basic Pharmaceutics
L. Dittert, section program chairman, helped develop the seven contributed papers sessions that were held on Monday through Thursday in the Conrad Hilton. The individuals who presided at the various sessions included W. Cressman, S. Yalkowsky, G. Zografi, A. DiSanto, J. Doluisio, C. Chong, T. Bates, S. Hem, A. Simonelli, H. Lambert, J. Robinson, J. Seitz and R. Castello. The multitude of interesting papers which were presented covered topics such as pharmacokinetics, drug metabolism and excretion, protein binding, drug stability, absorption and bioavailability. Sixty-two contributed papers were presented at other sessions during the week. Economics and Administrative Science
A symposium, arranged by program
Journal of the AMERICAN PHARMACEUTICAL ASSOCIATION
chairman Mickey C. Smith, was sponsored by the section on Tuesday, August 6. "The Quality of Pharmaceutical Services," Mickey C. !Smith presiding, presented A.J. Brands, E. Johnson, R. Jang, R.A. Jackson, A. I. Wertheimer; topics explored were the opportunity for pharmacy in PSROs, evaluation of pharmaceutical services and the quality of those services. On Wednesday morning, August 7, a contributed papers session was presided over by Mickey C. Smith. The nine presentations were given by P.J. Bush, H.F. Kabat, E.T. Kelly, W.M. Dickson, P. Amarinthnukrowh, R. A. Freeman, J.P. Gagnon, W.L. Hightower, A.I. Wertheimer. Nine other papers were presented at additional sessions. Industrial Pharmaceutical Technology
H. Wolkoff, newly installed chairman of the section, was IPT program chairman for the Chicago meeting. The first symposium, "Excipient Effects on Drug Availabilit}" was presided over by J.T. Dohiisio. Speakers included J.1. Lach on "Solid Dosage Forms," C.T. Rhodes on "Solutions and Suspensions" and R.E. Jones on "Topicals." S. Motola chaired the second symposium on "Implants-Theory, Design and Practice." This event featured papers by G.L. Flynn and R. Leininger as well as case histories by R.E. Willette, R. Buckles and A. Rubin. IPT sponsored five active discussion groups as follows"Expiration Dating and Storage Requirements," "International Pharmaceutical Research and Development,"
The APS Economics and Administrative Science section devoted its first session to a symposium on "The Quality of Pharmaceutical Services." Participating in the session were (from the left) Robert Brook, Mickey C. Smith, Albert 1. Wertheimer, Richard E. Johnson, Richard Jackson, Allen J. Brands, who delivered the keynote address, and Raymond Jang.
At its third session, the Academy ofPharmaceutical Sciences' Industrial Pharmaceutical Technology section conducted a discussion group on "Expiration Dating and Storage Requirements." At the head table are Daniel Banes (standing), who presided, and Ralph S. Levi, who was a speaker.
"Clinical Material Supply Program," "Pharmaceutical Research and Development's Responsibility to Protect In-Line Products," and "Consumer Products: Their Development and Market Evaluation." Nine contributed papers were also given at the Chicago meeting. The nearly 200 attendees at the annual IPT Luncheon heard honored guest APhA President George D. Denmark deliver greetings from the Association, and President George H. Schneller brought the good wishes of the Academy of Pharmaceutical Sciences. A highlight on the luncheon program was presentation of the IPT award for the Advancement of Industrial Pharmacy to Takeru Higuchi. The award, sponsored by Searle Laboratories, was presented by R.S. Levi, chairman of the IPT Committee on Awards. Mr. and Mrs. Higuchi were honored at a pre-
The third and fourth sessions of the APS Pharmacology and Toxicology section were devoted to a symposium entitled "Immunopharmacology: Experimental and Clinical Applications." Participants in the program included (from the left) Barry Hopkins, Edward J. Flynn, Robert J. Lefkowitz, M. James Freeman and Bruce H. Wainer.
luncheon reception through the courtesy of Alza Corporation. Medicinal Chemistry
J. Block, section program chairman, arranged two contributed paper sessions and one symposium on Monday, August 5. The symposium was held on "Current Topics in Prostaglandins." D. L. Venton, presiding, presented the three speakers for the meeting. John Paulsrud spoke on "The Prostaglandins: A Biochemical Review," Raphael Pappo presented "Synthesis and Properties of Novel Prostaglandin Analogs," and "Effect of Molecular Modification of Some Pharmaceutical and Biological Properties of Prostaglandins" was given by Walter Morozowich. A total of 18 scientific papers was presented during the sessions on Tuesday and Wednesday.
Pharmaceutical Analysis and Control
Program chairman S. Fusari coordinated a full-day sy:mposium entitled "Sampling and Sampling Plans." S. Fusari presided and presentations were made by J. T. Cartensen on "Sampling and Sampling Plans," J.V. Bergen on "Samples, Sampling, and Semantics," T. Byers concerning "FDA's Quality Assurance Program," T. DiGaetano on "Improving the Reliability of Sampling Plans Used for Manufacturing Processes and Standards," · and J.D. Haynes spoke on "Thoughts About Coritent Uniformity Tests Under Various Conditions." An active panel discussion occurred at the close of the symposium. A total of 21 papers was presented at three additional sessions and two of these sessions heard important papers on the analysis of drugs in biological fluids.
Seated at the head table at the American Society of Pharmacognosy's annual banquet were (from the left) John DiGiovanni, Elmore H. Taylor Mrs. Harry H.S. Fang, Norman R. Farnsworth, Harry H.S. Fong, Mrs. Norman R. Farnsworth, ASP President William J. Kelleher, Mrs. Elmore H. Taylor and Sidney J. Stohs. The dinner took place at the Millionaire's Club in downtown Chicago. Vol. NS14, No.9, September 1974
459
Pharmacology and Toxicology
Louis Diamond, section program chairman, arranged two symposia which were "Immunopharmacology: Experi. mental and Clinical Applications" and "The Beta Adrenergic Receptor" with William F. Bousquet and Raymond P. Ahlquist presiding. Those presenting papers at the symposia included MJ. Freeman, E.J. Flynn, R.J. Lefkowitz, B.H. Wainer, K. Bonese, B. Hopkins, J. Lindenbaum, ' R.P. Ahlquist, 1. J. McPhillips, R.R. Tuttle, L. Harris and O.J. Lorenzetti. Eighteen contributed papers were also presented during other sessions. The Millionaire's Club was the scene of the American S ociety of Pharmacognosy banquet where John DiGiovanni (left) received the Kilmer Prize. DiGiovanni, a senior at the University of Washington school of pharmacy, accepted the prize from Sidney J. Stohs, chairman of the Kilmer Prize committee .
The IPT Award, a plaque awarded for the advancement of industrial pharmacy, was presented to Takeru Higuchi (left) of the University of Kansas at the Industrial Pharmaceutical Technology section luncheon August 6. The award, sponsored by G. D. Searle & Company, was presented by Ralph S. Levi, past chairman of the IPT Section. Jacob L. Varsano (right) was chosen by the Academy of Pharmaceutical Sciences to receive the 1974 Ebert Prize awarded to the author of the most outstanding paper representing original research to appear in the Journal of PharSciences. maceutical Presenting the award at the APS luncheon are (from the left) George H. Schneller, Academy president, and Gordon L. Flynn, chairman of the Ebert Prize Committee.
Recipient of the Research Achievement A ward for Pharmaceutical and M edicinal Chemistry is Karl Folkers (right), University of Texas. The honor was awarded at the APS luncheon by (from the left) George H. Schneller, APS president, and James E. Gearien, chairman of the Medicinal Chemistry section. The award is sponsored by The Upjohn Com-
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The Research Achievement Award in Natural Products , sponsored by FMC Corporation , was presented to Norman R. Farnsworth (center) of the University of Illinois. Congratulating Farnsworth are George H. Schneller (leff) , APS president, and Elmore H. Taylor (right) , chairman of Pharmacognosy and Natural Products section. The presentation was made at the APS luncheon in the Conrad Hilton. 460
Journal of the AMERICAN PHARMACEUTICAL ASSOCIATION
Pharmacognosy and Natural Products
Under the coordination of program chairman J. Robbers, the Pharma· cognosy and Natural Products section held its scientific program and business meeting in conjunction with the meeting of the American Society of Pharmacognosy. At the meeting John DiGiovanni was presented the 1974 Kilmer Prize. The winner, who this year is a recent graduate of the school of pharmacy, University of Washington, presented his award-winning paper "Evaluation of Tyrosine Phenol-Lyase and Phenylalanine Ammonia-Lyase for Use in Malignant Melanoma," at the joint meeting. A symposium also was sponsored in three sessions during the joint meeting on "The Chemistry and Biological Activity of Natural Toxins." A total of 55 contributed papers was presented during 13 joint sessions of the two groups. The Academy and its officers wish to express their appreciation to the pharmaceutical manufacturing firms which so generously contributed toward support of the scientific program presented in Chicago. They are-Abbott Laboratories, Astra Pharmaceutical Products, Inc., Ayerst Laboratories , CibaBaxter Laboratories, Inc., Geigy Corp., Cooper Laboratories, Inc., Cutter Laboratories, Dow Chemical Company, Endo Laboratories, Inc., Hoechst Pharmaceuticals, Inc., Hoffmann-LaRoche, Inc., Lederle Laboratories, Inc., Eli Lilly & Co., McNeil Laboratories, Inc., Merck Sharp & Dohme, Miles Laboratories, Inc., Norwich Pharmaca] Company, Ortho Research Foundation, Pfizer, Inc., Pennwalt Corp., S.B. Penick & Co., Riker Laboratories, Inc., A.H. Robins, SandozWander, Inc., Searle Laboratories, Smith Kline & French Laboratories, E.R. Squibb & Sons, Inc., Sterling-Winthrop Research Institute, Stuart Pharmaceuticals, Syntex Laboratories, Inc., The Upjohn Company, Vick Divisions Research & Development, Warner-Lambert Co. and Wyeth Laboratories.
New officers of the Academy ofPharmaceutical Sciences are (from the left) William F. McGhan , executive secretary; James C. Boylan, vice president; Louis W. Busse, president; Dale E. Wurster, president-elect, and George H. Schneller, immediate past president.
ing followed the luncheon on August 7. President George H. Schneller presented his report to the membership, and also received the reports of the Academy committee chairmen. New officers of the Academy were installed-Louis W. Busse, president; Dale E. Wurster, president-elect; James C. Boylan, vice president; George H. Schneller, past president, and Patrick P. DeLuca, member-at-Iarge. Continuing members-atlarge on the executive committee are Arnold D. Marcus and George Zografi. The sections of the Academy sponsored 37 scientific sessions, and over 230 papers, coordinated through the Academy Program Committee, John Poole, chairman. Basic Pharmaceutics
L. Dittert, section program chairman, helped develop the seven contributed papers sessions that were held on Monday through Thursday in the Conrad Hilton. The individuals who presided at the various sessions included W. Cressman, S. Yalkowsky, G. Zografi, A. DiSanto, J. Doluisio, C. Chong, T. Bates, S. Hem, A. Simonelli, H. Lambert, J. Robinson, J. Seitz and R. Castello. The multitude of interesting papers which were presented covered topics such as pharmacokinetics, drug metabolism and excretion, protein binding, drug stability, absorption and bioavailability. Sixty-two contributed papers were presented at other sessions during the week. Economics and Administrative Science
A symposium, arranged by program
Journal of the AMERICAN PHARMACEUTICAL ASSOCIATION
chairman Mickey C. Smith, was sponsored by the section on Tuesday, August 6. "The Quality of Pharmaceutical Services," Mickey C. !Smith presiding, presented A.J. Brands, E. Johnson, R. Jang, R.A. Jackson, A. I. Wertheimer; topics explored were the opportunity for pharmacy in PSROs, evaluation of pharmaceutical services and the quality of those services. On Wednesday morning, August 7, a contributed papers session was presided over by Mickey C. Smith. The nine presentations were given by P.J. Bush, H.F. Kabat, E.T. Kelly, W.M. Dickson, P. Amarinthnukrowh, R. A. Freeman, J.P. Gagnon, W.L. Hightower, A.I. Wertheimer. Nine other papers were presented at additional sessions. Industrial Pharmaceutical Technology
H. Wolkoff, newly installed chairman of the section, was IPT program chairman for the Chicago meeting. The first symposium, "Excipient Effects on Drug Availabilit}" was presided over by J.T. Dohiisio. Speakers included J.1. Lach on "Solid Dosage Forms," C.T. Rhodes on "Solutions and Suspensions" and R.E. Jones on "Topicals." S. Motola chaired the second symposium on "Implants-Theory, Design and Practice." This event featured papers by G.L. Flynn and R. Leininger as well as case histories by R.E. Willette, R. Buckles and A. Rubin. IPT sponsored five active discussion groups as follows"Expiration Dating and Storage Requirements," "International Pharmaceutical Research and Development,"
The APS Economics and Administrative Science section devoted its first session to a symposium on "The Quality of Pharmaceutical Services." Participating in the session were (from the left) Robert Brook, Mickey C. Smith, Albert 1. Wertheimer, Richard E. Johnson, Richard Jackson, Allen J. Brands, who delivered the keynote address, and Raymond Jang.
At its third session, the Academy ofPharmaceutical Sciences' Industrial Pharmaceutical Technology section conducted a discussion group on "Expiration Dating and Storage Requirements." At the head table are Daniel Banes (standing), who presided, and Ralph S. Levi, who was a speaker.
"Clinical Material Supply Program," "Pharmaceutical Research and Development's Responsibility to Protect In-Line Products," and "Consumer Products: Their Development and Market Evaluation." Nine contributed papers were also given at the Chicago meeting. The nearly 200 attendees at the annual IPT Luncheon heard honored guest APhA President George D. Denmark deliver greetings from the Association, and President George H. Schneller brought the good wishes of the Academy of Pharmaceutical Sciences. A highlight on the luncheon program was presentation of the IPT award for the Advancement of Industrial Pharmacy to Takeru Higuchi. The award, sponsored by Searle Laboratories, was presented by R.S. Levi, chairman of the IPT Committee on Awards. Mr. and Mrs. Higuchi were honored at a pre-
The third and fourth sessions of the APS Pharmacology and Toxicology section were devoted to a symposium entitled "Immunopharmacology: Experimental and Clinical Applications." Participants in the program included (from the left) Barry Hopkins, Edward J. Flynn, Robert J. Lefkowitz, M. James Freeman and Bruce H. Wainer.
luncheon reception through the courtesy of Alza Corporation. Medicinal Chemistry
J. Block, section program chairman, arranged two contributed paper sessions and one symposium on Monday, August 5. The symposium was held on "Current Topics in Prostaglandins." D. L. Venton, presiding, presented the three speakers for the meeting. John Paulsrud spoke on "The Prostaglandins: A Biochemical Review," Raphael Pappo presented "Synthesis and Properties of Novel Prostaglandin Analogs," and "Effect of Molecular Modification of Some Pharmaceutical and Biological Properties of Prostaglandins" was given by Walter Morozowich. A total of 18 scientific papers was presented during the sessions on Tuesday and Wednesday.
Pharmaceutical Analysis and Control
Program chairman S. Fusari coordinated a full-day sy:mposium entitled "Sampling and Sampling Plans." S. Fusari presided and presentations were made by J. T. Cartensen on "Sampling and Sampling Plans," J.V. Bergen on "Samples, Sampling, and Semantics," T. Byers concerning "FDA's Quality Assurance Program," T. DiGaetano on "Improving the Reliability of Sampling Plans Used for Manufacturing Processes and Standards," · and J.D. Haynes spoke on "Thoughts About Coritent Uniformity Tests Under Various Conditions." An active panel discussion occurred at the close of the symposium. A total of 21 papers was presented at three additional sessions and two of these sessions heard important papers on the analysis of drugs in biological fluids.
Seated at the head table at the American Society of Pharmacognosy's annual banquet were (from the left) John DiGiovanni, Elmore H. Taylor Mrs. Harry H.S. Fang, Norman R. Farnsworth, Harry H.S. Fong, Mrs. Norman R. Farnsworth, ASP President William J. Kelleher, Mrs. Elmore H. Taylor and Sidney J. Stohs. The dinner took place at the Millionaire's Club in downtown Chicago. Vol. NS14, No.9, September 1974
459
Pharmacology and Toxicology
Louis Diamond, section program chairman, arranged two symposia which were "Immunopharmacology: Experi. mental and Clinical Applications" and "The Beta Adrenergic Receptor" with William F. Bousquet and Raymond P. Ahlquist presiding. Those presenting papers at the symposia included MJ. Freeman, E.J. Flynn, R.J. Lefkowitz, B.H. Wainer, K. Bonese, B. Hopkins, J. Lindenbaum, ' R.P. Ahlquist, 1. J. McPhillips, R.R. Tuttle, L. Harris and O.J. Lorenzetti. Eighteen contributed papers were also presented during other sessions. The Millionaire's Club was the scene of the American S ociety of Pharmacognosy banquet where John DiGiovanni (left) received the Kilmer Prize. DiGiovanni, a senior at the University of Washington school of pharmacy, accepted the prize from Sidney J. Stohs, chairman of the Kilmer Prize committee .
The IPT Award, a plaque awarded for the advancement of industrial pharmacy, was presented to Takeru Higuchi (left) of the University of Kansas at the Industrial Pharmaceutical Technology section luncheon August 6. The award, sponsored by G. D. Searle & Company, was presented by Ralph S. Levi, past chairman of the IPT Section. Jacob L. Varsano (right) was chosen by the Academy of Pharmaceutical Sciences to receive the 1974 Ebert Prize awarded to the author of the most outstanding paper representing original research to appear in the Journal of PharSciences. maceutical Presenting the award at the APS luncheon are (from the left) George H. Schneller, Academy president, and Gordon L. Flynn, chairman of the Ebert Prize Committee.
Recipient of the Research Achievement A ward for Pharmaceutical and M edicinal Chemistry is Karl Folkers (right), University of Texas. The honor was awarded at the APS luncheon by (from the left) George H. Schneller, APS president, and James E. Gearien, chairman of the Medicinal Chemistry section. The award is sponsored by The Upjohn Com-
~
The Research Achievement Award in Natural Products , sponsored by FMC Corporation , was presented to Norman R. Farnsworth (center) of the University of Illinois. Congratulating Farnsworth are George H. Schneller (leff) , APS president, and Elmore H. Taylor (right) , chairman of Pharmacognosy and Natural Products section. The presentation was made at the APS luncheon in the Conrad Hilton. 460
Journal of the AMERICAN PHARMACEUTICAL ASSOCIATION
Pharmacognosy and Natural Products
Under the coordination of program chairman J. Robbers, the Pharma· cognosy and Natural Products section held its scientific program and business meeting in conjunction with the meeting of the American Society of Pharmacognosy. At the meeting John DiGiovanni was presented the 1974 Kilmer Prize. The winner, who this year is a recent graduate of the school of pharmacy, University of Washington, presented his award-winning paper "Evaluation of Tyrosine Phenol-Lyase and Phenylalanine Ammonia-Lyase for Use in Malignant Melanoma," at the joint meeting. A symposium also was sponsored in three sessions during the joint meeting on "The Chemistry and Biological Activity of Natural Toxins." A total of 55 contributed papers was presented during 13 joint sessions of the two groups. The Academy and its officers wish to express their appreciation to the pharmaceutical manufacturing firms which so generously contributed toward support of the scientific program presented in Chicago. They are-Abbott Laboratories, Astra Pharmaceutical Products, Inc., Ayerst Laboratories , CibaBaxter Laboratories, Inc., Geigy Corp., Cooper Laboratories, Inc., Cutter Laboratories, Dow Chemical Company, Endo Laboratories, Inc., Hoechst Pharmaceuticals, Inc., Hoffmann-LaRoche, Inc., Lederle Laboratories, Inc., Eli Lilly & Co., McNeil Laboratories, Inc., Merck Sharp & Dohme, Miles Laboratories, Inc., Norwich Pharmaca] Company, Ortho Research Foundation, Pfizer, Inc., Pennwalt Corp., S.B. Penick & Co., Riker Laboratories, Inc., A.H. Robins, SandozWander, Inc., Searle Laboratories, Smith Kline & French Laboratories, E.R. Squibb & Sons, Inc., Sterling-Winthrop Research Institute, Stuart Pharmaceuticals, Syntex Laboratories, Inc., The Upjohn Company, Vick Divisions Research & Development, Warner-Lambert Co. and Wyeth Laboratories.